Colon and rectal surgery for cancer without mechanical bowel preparation: One-center randomized prospective trial

World Journal of Surgical Oncology

Research

Giampiero Damiani¹  Renato Scordamaglia¹  Edoardo Rimini¹  Emanuele Romairone¹  Stefano Scabini¹  Davide Pertile¹  Valter Ferrando¹ 

[1] Unit of Surgical Oncology, Department of Emato-Oncology, San Martino Hospital, Genoa, Italy;

关键词: Bowel Preparation;    Primary Anastomosis;    Mechanical Bowel Preparation;    Mechanical Preparation;    Elective Colon;   

DOI  :  10.1186/1477-7819-8-35

 received in 2010-02-07, accepted in 2010-04-30,  发布年份 2010

来源: Springer

【 摘 要 】

BackgroundMechanical bowel preparation is routinely done before colon and rectal surgery, aimed at reducing the risk of postoperative infectious complications. The aim of the study was to assess whether elective colon and rectal surgery can be safely performed without preoperative mechanical bowel preparation.MethodsPatients undergoing elective colon and rectal resections with primary anastomosis were prospectively randomized into two groups. Group A had mechanical bowel preparation with polyethylene glycol before surgery, and group B had their surgery without preoperative mechanical bowel preparation. Patients were followed up for 30 days for wound, anastomotic, and intra-abdominal infectious complications.ResultsTwo hundred forty four patients were included in the study, 120 in group A and 124 in group B. Demographic characteristics, type of surgical procedure and type of anastomosis did not significantly differ between the two groups. There was no difference in the rate of surgical infectious complications between the two groups but the overall infectious complications rate was 20.0% in group A and 11.3% in group B (p .05). Wound infection (p = 0.18), anastomotic leak (p = 0.52), and intra-abdominal abscess (p = 0.36) occurred in 9.2%, 5.8%, and 5.0% versus 4.8%, 4.0%, and 2.4%, respectively. No mechanical bowel preparation seems to be safe also in rectal surgery.ConclusionsThese results suggest that elective colon and rectal surgery may be safely performed without mechanical preparation.

【 授权许可】

CC BY   
© Scabini et al; licensee BioMed Central Ltd. 2010