Automated analysis of color tissue Doppler velocity recordings of the fetal myocardium using a new algorithm

Cardiovascular Ultrasound

Research

Peter Lindgren¹  Kjerstin Ferm-Widlund¹  Magnus Westgren²  Lotta Herling³  Jonas Johnson⁴  Ganesh Acharya⁵ 

[1] Centre for Fetal Medicine, Department of Obstetrics and Gynecology, Karolinska University Hospital, Stockholm, Sweden;Centre for Fetal Medicine, Department of Obstetrics and Gynecology, Karolinska University Hospital, Stockholm, Sweden;Department of Clinical Science, Intervention and Technology - CLINTEC, Karolinska Institute, Stockholm, Sweden;Centre for Fetal Medicine, Department of Obstetrics and Gynecology, Karolinska University Hospital, Stockholm, Sweden;University Hospital of Northern Norway, Tromsø, Norway;Department of Clinical Science, Intervention and Technology - CLINTEC, Karolinska Institute, Stockholm, Sweden;Department of Medical Engineering School of Technology and Health, KTH Royal Institute of Technology, Stockholm, Sweden;University Hospital of Northern Norway, Tromsø, Norway;Department of Clinical Science, Intervention and Technology - CLINTEC, Karolinska Institute, Stockholm, Sweden;Department of Clinical Medicine, UiT- The Arctic University of Norway, Tromsø, Norway;

关键词: Tissue Doppler imaging;    Fetal cardiac function;    Region of interest (ROI);    Automated algorithm;   

DOI  :  10.1186/s12947-015-0034-3

 received in 2015-06-10, accepted in 2015-08-14,  发布年份 2015

来源: Springer

【 摘 要 】

BackgroundTissue Doppler imaging (TDI) can be used to assess fetal cardiac function and it has been shown to detect changes associated with hypoxia in animal models. However, the analysis is cumbersome and time consuming. The main objective of this study was to evaluate the feasibility of a new algorithm developed for the automated analysis of color TDI velocity recordings of the fetal myocardium. Furthermore, we wanted to assess the effect of different sizes of region of interests (ROI) on the measurement of cardiac cycle time intervals and myocardial velocities at different gestations.MethodsThis study included analysis of 261 TDI velocity traces obtained from 17 fetal echocardiographic examinations performed longitudinally on five pregnant women. Cine-loops of fetal cardiac four chamber view were recorded with color overlay in TDI mode and stored for off-line analysis. ROIs of different sizes were placed at the level of the atrioventricular plane in the septum and in the right and left ventricular walls of the fetal heart. An automated algorithm was then used for the analysis of velocity traces.ResultsOut of the total 261 velocity traces, it was possible to analyze 203 (78 %) traces with the automated algorithm. It was possible to analyze 93 % (81/87) of traces recorded from the right ventricular wall, 82 % (71/87) from the left ventricular wall and 59 % (51/87) from the septum. There was a trend towards decreasing myocardial velocities with increasing ROI length. However, the cardiac cycle time intervals were similar irrespective of which ROI size was used.ConclusionsAn automated analysis of color TDI fetal myocardial velocity traces seems feasible, especially for measuring cardiac cycle time intervals, and has the potential for clinical application.

【 授权许可】

CC BY   
© Herling et al. 2015