Papulonodular mucinosis, Guillain-Barré syndrome and nephrotic syndrome in a patient with systemic lupus erythematosus: a case report

BMC Nephrology

Case Report

Lifang Gao¹  Chen Wang¹  Lihua Wang²  Xiaole Su²  Xi Qiao²  Jing Li² 

[1] Pathology Division, Shanxi Medical University Second Hospital, Shanxi Province Kidney Pathology Centre, No.382, Wuyi Road, Xinghualing Distirct, Taiyuan, Shanxi Province, China;Renal Division, Shanxi Medical University Second Hospital, Shanxi Kidney Disease Institute, No.382, Wuyi Road, Xinghualing Distirct, Taiyuan, Shanxi Province, China;

关键词: Nephrotic syndrome;    Papulonodular mucinosis;    Guillain-Barré syndrome;    Systemic lupus erythematosus;   

DOI  :  10.1186/s12882-017-0458-0

 received in 2015-10-02, accepted in 2017-01-23,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundAwareness of the spectrum of clinical manifestations of systemic lupus erythematosus (SLE), especially uncommon changes, is essential for diagnosis and effective management of patients.Case presentationA 26-year-old Chinese man with SLE initially manifested cutaneous papulonodular mucinosis and developed acute Guillain-Barré syndrome and class V lupus nephritis 2 years later. His cutaneous nodules had not been idententified for 2 years and were resected by surgical procedures twice until SLE was diagnosed. The kidney biopsy revealed class V lupus nephritis. The patient responded well to a short course of intravenous immunoglobulins and his muscle strength almost completely recovered. So far, he has undergone five cycles of cyclophosphamide combined with hydroxychloroquine and tapering prednisone, resulting in partial remission of lupus nephritis and disappearance of hypocomplementemia.ConclusionWe reported a rare case of male patient with SLE with manifestation of class V lupus nephritis, Guillain-Barré syndrome and papulonodular mucinosis.

【 授权许可】

CC BY   
© The Author(s). 2017