Psychosocial functioning in patients with treatment-resistant depression after group cognitive behavioral therapy

BMC Psychiatry

Research Article

Shinpei Yoshimura¹  Atsuo Yoshino¹  Akiko Kinoshita¹  Shigeto Yamawaki¹  Yasumasa Okamoto¹  Yoshihiko Kunisato¹  Miki Matsunaga²  Shin-ichi Suzuki³ 

[1] Department of Psychiatry and Neurosciences, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3, Kasumi, 734-8551, Minami-ku, Hiroshima, Japan;Department of Psychiatry and Neurosciences, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3, Kasumi, 734-8551, Minami-ku, Hiroshima, Japan;Department of Social and Clinical Psychology, Faculty of Contemporary Culture, Hijiyama University, 4-1-1, Ushitashinmachi, 732-8509, Higashi-ku, Hiroshima, Japan;Faculty of Human Sciences, Waseda University, 2-579-15, Mikajima, 359-1192, Tokorozawa, Saitama, Japan;

关键词: Depressive Symptom;    Cognitive Behavioral Therapy;    Physical Component Summary;    Mental Component Summary;    Mental Component Summary Score;   

DOI  :  10.1186/1471-244X-10-22

 received in 2009-07-06, accepted in 2010-03-16,  发布年份 2010

来源: Springer

【 摘 要 】

BackgroundAlthough patients with Treatment Resistant Depression (TRD) often have impaired social functioning, few studies have investigated the effectiveness of psychosocial treatment for these patients. We examined whether adding group cognitive behavioral therapy (group-CBT) to medication would improve both the depressive symptoms and the social functioning of patient with mild TRD, and whether any improvements would be maintained over one year.MethodsForty-three patients with TRD were treated with 12 weekly sessions of group-CBT. Patients were assessed with the Global Assessment of Functioning scale (GAF), the 36-item Short-Form Health Survey (SF-36), the Hamilton Rating Scale for Depression (HRSD), the Dysfunctional Attitudes Scale (DAS), and the Automatic Thought Questionnaire-Revised (ATQ-R) at baseline, at the termination of treatment, and at the 12-month follow-up.ResultsThirty-eight patients completed treatment; five dropped out. For the patients who completed treatment, post-treatment scores on the GAF and SF-36 were significantly higher than baseline scores. Scores on the HRSD, DAS, and ATQ-R were significantly lower after the treatment. Thus patients improved on all measurements of psychosocial functioning and mood symptoms. Twenty patients participated in the 12-month follow-up. Their improvements for psychosocial functioning, depressive symptoms, and dysfunctional cognitions were sustained at 12 months following the completion of group-CBT.ConclusionsThese findings suggest a positive effect that the addition of cognitive behavioural group therapy to medication on depressive symptoms and social functioning of mildly depressed patients, showing treatment resistance.

【 授权许可】

Unknown   
© Matsunaga et al; licensee BioMed Central Ltd. 2010. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.