The application of titanium dioxide, zinc oxide, fullerene, and graphene nanoparticles in photodynamic therapy

Cancer Nanotechnology

Review

Thibault Roques-Carmes¹  Francis Baros¹  Zahraa Youssef¹  Ludovic Colombeau¹  Céline Frochot¹  Régis Vanderesse²  Samir Acherar²  Amirah Mohd Gazzali³  Joumana Toufaily⁴  Tayssir Hamieh⁴  Habibah Wahab⁵ 

[1] Laboratoire Réactions et Génie des Procédés, Université de Lorraine-CNRS, UMR 7274, BP 20451, 1 rue Grandville, 54001, Nancy Cedex, France;Laboratoire de Chimie Physique Macromoléculaire, Université de Lorraine-CNRS, UMR 7375, BP 20451, 1 rue Grandville, 54001, Nancy Cedex, France;Laboratoire de Chimie Physique Macromoléculaire, Université de Lorraine-CNRS, UMR 7375, BP 20451, 1 rue Grandville, 54001, Nancy Cedex, France;School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800, Penang, Malaysia;Laboratory of Materials, Catalysis, Environment and Analytical Methods, Faculty of Sciences I, Lebanese University, Campus Rafic Hariri, Beyrouth, Lebanon;School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800, Penang, Malaysia;

关键词: Nanoparticles;    Photodynamic therapy;    Titanium dioxide;    Zinc oxide;    Fullerene;    Graphene;   

DOI  :  10.1186/s12645-017-0032-2

 received in 2017-03-20, accepted in 2017-10-06,  发布年份 2017

来源: Springer

【 摘 要 】

Nanoparticles (NPs) have been shown to have good ability to improve the targeting and delivery of therapeutics. In the field of photodynamic therapy (PDT), this targeting advantage of NPs could help ensure drug delivery at specific sites. Among the commonly reported NPs for PDT applications, NPs from zinc oxide, titanium dioxide, and fullerene are commonly reported. In addition, graphene has also been reported to be used as NPs albeit being relatively new to this field. In this context, the present review is organized by these different NPs and contains numerous research works related to PDT applications. The effectiveness of these NPs for PDT is discussed in detail by collecting all essential information described in the literature. The information thus assembled could be useful in designing new NPs specific for PDT and/or PTT applications in the future.

【 授权许可】

CC BY   
© The Author(s) 2017