Malignant fibrous histiocytoma of the distal femur after an arthroscopic anterior cruciate ligament reconstruction: A case report and a review of the literature

BMC Cancer

Case Report

Thomas J Heyse¹  Susanne Fuchs-Winkelmann¹  Markus D Schofer¹  Turgay Efe¹  Jan Schmitt¹  Peter Rexin² 

[1] Department of Orthopaedics and Rheumatology, University Hospital Marburg, 35043, Baldingerstrasse, Marburg, Germany;Institute of Pathology, University Hospital Marburg, Baldingerstrasse, 35043, Marburg, Germany;

关键词: Anterior Cruciate Ligament;    Anterior Cruciate Ligament Reconstruction;    Malignant Fibrous Histiocytoma;    Medial Femoral Condyle;    Semitendinosus Tendon;   

DOI  :  10.1186/1471-2407-10-264

 received in 2009-11-24, accepted in 2010-06-08,  发布年份 2010

来源: Springer

【 摘 要 】

BackgroundMalignant degeneration in association with orthopaedic implants is a known but rare complication. To our knowledge, no case of osseous malignant fibrous histiocytoma after anterior cruciate ligament reconstruction is reported in the literature.Case presentationWe report a 29-year-old male Turkish patient who presented with severe pain in the operated knee joint 40 months after arthroscopic anterior cruciate ligament reconstruction. X-ray and MR imaging showed a large destructive tumor in the medial femoral condyle. Biopsy determined a malignant fibrous histiocytoma. After neoadjuvant chemotherapy, wide tumor resection and distal femur reconstruction with a silver-coated non-cemented tumor knee joint prosthesis was performed. Adjuvant chemotherapy was continued according to the EURAMOS 1 protocol.ConclusionsThough secondary malignant degeneration after orthopaedic implants or prostheses is not very likely, the attending physician should take this into consideration, especially if symptoms worsen severely over a short period of time.

【 授权许可】

CC BY   
© Efe et al; licensee BioMed Central Ltd. 2010