Secular trends of macrosomia in southeast China, 1994-2005

BMC Public Health

Research Article

Jun Zhang¹  Zhu Li²  Yanyu Lu³  Xinrong Lu⁴  Wei Xi⁵ 

[1] MOE-Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, 200092, Shanghai, China;School of Public Health, Peking University Health Science Center, 100191, Beijing, China;School of Public Health, Peking University Health Science Center, 100191, Beijing, China;Capital Institute of Pediatrics, 100020, Beijing, China;School of Public Health, Peking University Health Science Center, 100191, Beijing, China;Chinese Jilin Center For Disease Control and Prevention, 130062, Changchun, China;School of Public Health, Peking University Health Science Center, 100191, Beijing, China;School of Public Health, Tianjin Medical University, 300100, Tianjin, China;

关键词: Birth Weight;    Gestational Weight Gain;    Prepregnancy Body Mass Index;    Maternal Body Mass Index;    Maternal Height;   

DOI  :  10.1186/1471-2458-11-818

 received in 2011-02-11, accepted in 2011-10-20,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundThe rate of macrosomia (birth weight≥4, 000 g) increased over the past four decades in many parts of the world. Macrosomia is associated not only with higher risks of maternal and neonatal complications but also with health risks in adulthood. We examined trends in neonatal macrosomia and large-for-gestational-age (LGA) births among singleton, live, term and postterm births (≥37 complete weeks' gestation) in southeast China from 1994 to 2005 and explored possible causes of the temporal trends.MethodsData from Perinatal Health Care Surveillance System in 12 cities and counties in southeast China were analyzed for trends in birth weight, neonatal macrosomia and LGA from 1994 to 2005. A total of 594, 472 singleton live births were included. We conducted multiple logistic regression analyses to relate these trends to changes in maternal and pregnancy characteristics.ResultsThe rate of macrosomia rose from 6.00% in 1994 to 8.49% in 2000 and then levelled off to 7.83% in 2005. Similar trends were observed in mean birth weight. The incidence of LGA births increased continuously from 13.72% in 1994 to 18.08% in 2000, but the LGA rate remained relatively stable from 2002 to 2005. There was a decrease in gestational age and a significant increase in frequency of prelabor caesarean delivery from 1994 to 2005. In an adjusted multivariable model, the increase in LGA rate from 1994 to 2000 was associated with increasing net gestational weight gain, maternal age, maternal height and maternal education. But they didn't fully explain the increase. The trends of 2002-2005 LGA declined after adjusted for maternal and neonatal characteristics.ConclusionsIn southeast China, the incidence of macrosomia increased from 1994 to 2000 was mainly related to increasing net gestational weight gain. The incidence of macrosomia has levelled off in recent years partly due to increasing use of prelabor caesarean delivery and earlier delivery and partly due to moderation of gestational weight gain.

【 授权许可】

Unknown   
© Lu et al; licensee BioMed Central Ltd. 2011. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.