Association between obesity indices and cardiovascular risk factors in late adolescence in the Seychelles

BMC Pediatrics

Research Article

Gary Myers¹  Tiphaine Arlabosse²  Pascal Bovet³  Bharathi Viswanathan⁴ 

[1] Department of Child Neurology, University of Rochester Medical Center, Rochester, NY, USA;Institute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital, Lausanne, Switzerland;Institute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital, Lausanne, Switzerland;Section of Noncommunicable Diseases, Ministry of Health, Victoria, Republic of Seychelles;Section of Noncommunicable Diseases, Ministry of Health, Victoria, Republic of Seychelles;

关键词: Obesity;    Body mass index (BMI);    Cardiovascular risk factors;    Screening;    Youth;    Adolescents;    Young adults;    Africa;   

DOI  :  10.1186/1471-2431-12-176

 received in 2012-05-19, accepted in 2012-11-04,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundThe ability of different obesity indices to predict cardiovascular risk is still debated in youth and few data are available in sub Saharan Africa. We compared the associations between several indices of obesity and cardiovascular risk factors (CVRFs) in late adolescence in the Seychelles.MethodsWe measured body mass index (BMI), waist circumference, waist/hip ratio (WHiR), waist/height ratio (WHtR) and percent fat mass (by bioimpedance) and 6 CVRFs (blood pressure, LDL-cholesterol, HDL-cholesterol, triglycerides, fasting blood glucose and uric acid) in 423 youths aged 19–20 years from the general population.ResultsThe prevalence of overweight/obesity and several CVRFs was high, with substantial sex differences. Except for glucose in males and LDL-cholesterol in females, all obesity indices were associated with CVRFs. BMI consistently predicted CVRFs at least as well as the other indices. Linear regression on BMI had standardized regression coefficients of 0.25-0.36 for most CVRFs (p<0.01) and ROC analysis had an AUC between 60%-75% for most CVRFs. BMI also predicted well various combinations of CVRFs: 36% of male and 16% of female lean subjects (BMI P90).ConclusionThere was an elevated prevalence of obesity and of several CVRFs in youths in Seychelles. BMI predicted single or combined CVRFs at least as well as other simple obesity indices.

【 授权许可】

CC BY   
© Bovet et al.; licensee BioMed Central Ltd. 2012