In search of quality evidence for lifestyle management and glycemic control in children and adolescents with type 2 diabetes: A systematic review

BMC Pediatrics

Research Article

Steven T Johnson¹  Geoff DC Ball²  Amanda S Newton²  Mary M Jetha²  Terry TK Huang³  Paul W Franks⁴  Jeanette Buckingham⁵  Meera Chopra⁶ 

[1] Centre for Nursing & Health Studies, Faculty of Health Disciplines, 1 University Drive Athabasca University, Athabasca, AB, Canada;Department of Pediatrics, University of Alberta, 8213 Aberhart Centre, 11402 University Avenue, T6G 2P3, Edmonton, AB, Canada;Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA;Genetic Epidemiology and Clinical Research Group, Department of Public Health and Clinical Medicine, Division of Medicine, Umeå University Hospital, Umeå, Sweden;John W. Scott Health Sciences Library, University of Alberta, WMC 2K4.01, T6G 2R7, Edmonton, AB, Canada;Mount Sinai Hospital, Joseph and Wolf Lebovic Health Complex, 60 Murray Street, 4th Floor, M5T 3L9, Toronto, Ontario, Canada;

关键词: Glycemic Control;    Lifestyle Modification;    Good Glycemic Control;    Pediatric Weight Management;    Quality Index Score;   

DOI  :  10.1186/1471-2431-10-97

 received in 2010-04-23, accepted in 2010-12-23,  发布年份 2010

来源: Springer

【 摘 要 】

BackgroundOur purpose was to evaluate the impact of lifestyle behavior modification on glycemic control among children and youth with clinically defined Type 2 Diabetes (T2D).MethodsWe conducted a systematic review of studies (randomized trials, quasi-experimental studies) evaluating lifestyle (diet and/or physical activity) modification and glycemic control (HbA1c). Our data sources included bibliographic databases (EMBASE, CINAHL®, Cochrane Library, Medline®, PASCAL, PsycINFO®, and Sociological Abstracts), manual reference search, and contact with study authors. Two reviewers independently selected studies that included any intervention targeting diet and/or physical activity alone or in combination as a means to reduce HbA1c in children and youth under the age of 18 with T2D.ResultsOur search strategy generated 4,572 citations. The majority of citations were not relevant to the study objective. One study met inclusion criteria. In this retrospective study, morbidly obese youth with T2D were treated with a very low carbohydrate diet. This single study received a quality index score of < 11, indicating poor study quality and thus limiting confidence in the study's conclusions.ConclusionsThere is no high quality evidence to suggest lifestyle modification improves either short- or long-term glycemic control in children and youth with T2D. Additional research is clearly warranted to define optimal lifestyle behaviour strategies for young people with T2D.

【 授权许可】

Unknown   
© Johnson et al; licensee BioMed Central Ltd. 2010. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.