One-year effects of two intensive inpatient treatments for severely obese children and adolescents

BMC Pediatrics

Research Article

Sabine Makkes¹  Carry M. Renders¹  Judith E. Bosmans¹  Trynke Hoekstra²  Jacob C. Seidell³  Olga H. van der Baan-Slootweg⁴ 

[1] Department of Health Sciences and the EMGO Institute for Health and Care Research, VU University Amsterdam, Amsterdam, The Netherlands;Department of Health Sciences and the EMGO Institute for Health and Care Research, VU University Amsterdam, Amsterdam, The Netherlands;Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands;Department of Health Sciences and the EMGO Institute for Health and Care Research, VU University Amsterdam, Amsterdam, The Netherlands;Department of Health Sciences, Faculty of Earth and Life Sciences, Section Prevention and Public Health, VU University Amsterdam, De Boelelaan 1085, 1081 HV, Amsterdam, The Netherlands;Merem Childhood Obesity Center, Heideheuvel, Hilversum, The Netherlands;

关键词: Morbid obesity;    Child;    Adolescent;    Lifestyle;    Treatment effectiveness;   

DOI  :  10.1186/s12887-016-0659-x

 received in 2016-02-24, accepted in 2016-07-26,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundIntensive inpatient lifestyle treatment may be a suitable alternative for severely obese children and adolescents who do not benefit from ambulatory obesity treatment.The aim was to evaluate the effectiveness of two intensive one-year lifestyle treatments with varying inpatient periods for severely obese children and adolescents with regard to SDS-BMI and cardiometabolic risk factors.MethodsThe study was designed as a randomized controlled trial with two active treatment groups.Eighty participants (8–19 years) with severe obesity received treatment at a specialized childhood obesity center in the Netherlands. Severe obesity was defined as a SDS-BMI ≥ 3.0 or a SDS-BMI ≥ 2.3 in combination with obesity-related comorbidity.Participants received an intensive one-year lifestyle treatment with an inpatient period of either two months and biweekly return visits during the next four months (short-stay group) or six months (long-stay group), both followed by six monthly return visits.Outcomes were assessed at baseline, six and 12 months and included SDS-BMI as primary outcome and cardiometabolic risk factors such as SDS-waist circumference, systolic- and diastolic blood pressure, and blood measurements as secondary outcomes.To evaluate differences in the course of the primary- and secondary outcomes over time between the two treatment groups, Generalized Estimating Equations (GEE) were performed.ResultsNo differences in the course of SDS-BMI or secondary outcomes over time were found between the two treatment groups after one year of treatment. SDS-BMI decreased statistically significantly after one year of treatment compared with baseline in both groups (0.33 (0.48) in the short-stay and 0.52 (0.49) in the long-stay group). Similar results were found for SDS-waist circumference, diastolic blood pressure and HDL-cholesterol.ConclusionsSince there were no significant differences in effects between the short- and long-stay treatment and considering the burden of the long-stay treatment for children and families, we recommend implementation of the short-stay treatment.Trial registrationNetherlands Trial Register NTR1678, registered 20-Feb-2009

【 授权许可】

CC BY   
© The Author(s). 2016