Porencephaly and psychosis: a case report and review of the literature

BMC Psychiatry

Case Report

Emmanouil N Rizos¹  Athanassios Douzenis¹  Athanasia Papadopoulou¹  Lefteris Lykouras¹  Matilda Papathanasiou² 

[1] 2nd Department of Psychiatry, University of Athens Medical School, "Attikon" General Hospital, 1 Rimini st Athens, 12462, Greece;2nd Department of Radiology, University of Athens Medical School, "Attikon" General Hospital, 1 Rimini st Athens, 12462, Greece;

关键词: Olanzapine;    Psychotic Symptom;    Medial Temporal Lobe;    Arachnoid Cyst;    Auditory Hallucination;   

DOI  :  10.1186/1471-244X-10-19

 received in 2009-10-08, accepted in 2010-03-02,  发布年份 2010

来源: Springer

【 摘 要 】

BackgroundMalformations of the cerebral cortex are often associated with developmental delay and psychoses. Porencephaly is a rare congenital disorder of central nervous system involving a cyst or a cavity filled with cerebrospinal fluid, in brain's parenchyma.Case presentationWe present a 25 years old woman with her first psychotic episode. She also suffers from porencephaly in the frontotemporal lobes region. It is emphasized that the two consistently abnormal brain regions in schizophrenia research had significant damage in this patient since birth. There is a total of only five cases of schizencephaly or porencephaly associated with psychosis in the scientific literature. Their clinical characteristics as well as the imaging results are described.ConclusionIt is unclear if porencephaly and psychosis concur by chance or are causally related. The area where the porencephalic cysts appear seems to be of relevance. This case highlights the need for further research.

【 授权许可】

CC BY   
© Douzenis et al; licensee BioMed Central Ltd. 2010