Rapid deterioration of Mooren’s ulcers after conjunctival flap: a review of 2 cases

BMC Ophthalmology

Case Report

Caiyuan Du¹  Yuqing Deng²  Saiqun Li²  Jing Zhong²  Haixiang Huang²  Bowen Wang²  Ling Chen²  Jin Yuan² 

[1] Allad Eye Hospital, 524043, Zhanjiang, China;State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 510060, Guangzhou, China;

关键词: Mooren’s ulcer;    Conjunctival flap;    Keratoplasty;    Case report;   

DOI  :  10.1186/s12886-017-0488-1

 received in 2016-07-07, accepted in 2017-06-08,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundConjunctival flaps are a widely used treatment for numerous corneal ulcers that are caused by microorganismal infections. However, whether it can be performed on immune-mediated corneal ulcers is controversial.Case presentationWe present two cases of Mooren’s ulcer that were treated using conjunctival flap in an attempt to prevent further corneal perforation at their local hospital. A rapid acceleration in ulcer progression was observed after a conjunctival flap was applied. Ultimately, the two patients underwent corneal transplantation, which required the postoperative use of topical immunosuppressants and resulted in a final cure. In the current report, we also discussed this incorrect surgical choice via a review of conventional interventions that are used to treat Mooren’s ulcer.ConclusionsThese two cases demonstrate that keratoplasty combined with topical immunosuppressants is effective in treating Mooren’s ulcer. Application of conjunctival flaps or autografting could promote progression of ulceration in Mooren’s ulcers.

【 授权许可】

CC BY   
© The Author(s). 2017