The prevalence of hyperuricemia in China: a meta-analysis

BMC Public Health

Research Article

Nie HW¹  Yue WW²  Liu CX²  Zhao HN²  Yin J²  Jia RY²  Wang T²  Yu HP²  Liu B² 

[1] Department of Public Health, The Second Affiliated Hospital of Soochow University, Sanxiang Road, 215000, Suzhou, China;Jinan Institute of Cardiovascular Disease, The Fourth People's Hospital of Jinan, Shifan Road, 250031, Jinan, China;

关键词: Gout;    Hyperuricemia;    Serum Uric Acid Level;    Chinese Mainland;    Multiple Risk Factor Intervention Trial;   

DOI  :  10.1186/1471-2458-11-832

 received in 2011-03-21, accepted in 2011-10-27,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundThe prevalence of hyperuricemia varied in different populations and it appeared to be increasing in the past decades. Recent studies suggest that hyperuricemia is an independent risk factor for cardiovascular disease. However, there has not yet been a systematic analysis of the prevalence of hyperuricemia in China.MethodsEpidemiological investigations on hyperuricemia in China published in journals were identified manually and on-line by using CBMDISC, Chongqing VIP database and CNKI database. Those Reported in English journals were identified using MEDLINE database. Selected studies had to describe an original study defined by strict screening and diagnostic criteria. The fixed effects model or random effects model was employed according to statistical test for homogeneity.ResultsFifty-nine studies were selected, the statistical information of which was collected for systematic analysis. The results showed that the pooled prevalence of hyperuricemia in male was 21.6% (95%CI: 18.9%-24.6%), but it was only 8.6% (95%CI: 8.2%-10.2%) in female. It was found that thirty years was the risk point age in male and it was fifty years in female.ConclusionsThe prevalence of hyperuricemia is different as the period of age and it increases after 30 years in male and 50 in female. Interventions are necessary to change the risk factors before the key age which is 30 years in male and 50 in female.

【 授权许可】

Unknown   
© B et al; licensee BioMed Central Ltd. 2011. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.