Adiposity markers and lung function in smokers: a cross-sectional study in a Mediterranean population

BMC Pulmonary Medicine

Research Article

Gemma Flores-Mateo¹  Josep Basora-Gallisಠ Estefania Aparicio-Llopis³  Cristina Jardí-Piñana³  Rosa Solà-Alberich⁴  Mar Sorlí-Aguilar⁵  Francisco Martín-Luján⁶ 

[1] Primary Healthcare Research Support Unit Tarragona-Reus, Institut Universitari d’Investigació en Atenció Primària Jordi Gol (IDIAP Jordi Gol), Reus, Spain;Primary Healthcare Research Support Unit Tarragona-Reus, Institut Universitari d’Investigació en Atenció Primària Jordi Gol (IDIAP Jordi Gol), Reus, Spain;School of Medicine and Health Sciences, Universitat Rovira i Virgili, Tarragona, Spain;CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III (ISCIII), Madrid, Spain;School of Medicine and Health Sciences, Universitat Rovira i Virgili, Tarragona, Spain;School of Medicine and Health Sciences, Universitat Rovira i Virgili, Tarragona, Spain;NFOC group School of Medicine and Health Sciences, Universitat Rovira i Virgili, Tarragona, Spain;Study Group on Respiratory Tract Diseases (GEPAR), Institut Universitari d’Investigació en Atenció Primària Jordi Gol (IDIAP Jordi Gol), Barcelona, Spain;Primary Healthcare Research Support Unit Tarragona-Reus, Institut Universitari d’Investigació en Atenció Primària Jordi Gol (IDIAP Jordi Gol), Reus, Spain;Study Group on Respiratory Tract Diseases (GEPAR), Institut Universitari d’Investigació en Atenció Primària Jordi Gol (IDIAP Jordi Gol), Barcelona, Spain;School of Medicine and Health Sciences, Universitat Rovira i Virgili, Tarragona, Spain;CAP Sant Pere - Institut Català de la Salut, C/Camí de Riudoms, 53-55, 43203, Reus, Tarragona, Spain;

关键词: Lung function test;    Overweight;    Obesity;    Waist circumference;    Tobacco smoke;   

DOI  :  10.1186/s12890-016-0341-y

 received in 2016-04-07, accepted in 2016-12-02,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundThe aim of this study was to assess the association of key adiposity markers with lung function in smokers without respiratory disease in a Mediterranean population.MethodsWe performed a cross-sectional study with baseline data from a representative sample of the ESPITAP study in Spain. Participants were 738 smokers (52.3% men) without respiratory disease, aged 35 to 70, selected from 12 primary health care centres. We assessed weight, height, body mass index (BMI), waist circumference (WC) and waist-to-height ratio (WHtR). The pulmonary functional parameters were forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1) and FEV1/FVC ratio.ResultsIn this cohort of smokers, 22.2% of individuals had central obesity. FVC% was inversely associated with all anthropometric measures (BMI, WC and WHtR) in the overall population and in men; in women, only BMI was associated with FVC%. FEV1% was inversely associated to BMI and WC in the overall population, and to all anthropometric measures in men. Furthermore, both BMI and obesity were positively associated with FEV1/FVC ratio overall and when stratified by sex; this suggests a restrictive pattern explained by the altered ventilator mechanics experienced by people with obesity.ConclusionIn a Mediterranean population of smokers without respiratory symptoms, abdominal obesity, evaluated not only by BMI and WC but also WHtR, is inversely associated with lung function. Fat distribution appears more strongly related to pulmonary function parameters in men than in women. In smokers with high values for WC, WHtR and BMI, assessment of lung function is recommended.Trial registrationCurrent Controlled Trials NCT01194596. Registered 2 September 2010.

【 授权许可】

CC BY   
© The Author(s). 2016