Diabetes susceptibility in ethnic minority groups from Turkey, Vietnam, Sri Lanka and Pakistan compared with Norwegians - the association with adiposity is strongest for ethnic minority women

BMC Public Health

Research Article

Gerd Holmboe-Ottesen¹  Anne Karen Jenum²  Kåre Inge Birkeland³  Bernadette Nirmar Kumar⁴  Ingar Morten K Holme⁵  Lien My Diep⁶ 

[1] Department of Community Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway;Department of Endocrinology, Oslo University Hospital, Aker, Oslo, Norway;Department of General Practice, Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway;Faculty of Health Sciences, Oslo and Akershus University College, Oslo, Norway;Department of Endocrinology, Oslo University Hospital, Aker, Oslo, Norway;Faculty of Medicine, University of Oslo, Oslo, Norway;Norwegian Centre for Minority Health Research, Oslo University Hospital, Oslo, Norway;Norwegian University of Sport and Physical Education, Oslo, Norway;Oslo University Hospital, Oslo, Norway;

关键词: Diabetes;    Ethnicity;    Adiposity;    Socioeconomic position;    Life course;   

DOI  :  10.1186/1471-2458-12-150

 received in 2011-07-07, accepted in 2012-03-01,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundThe difference in diabetes susceptibility by ethnic background is poorly understood. The aim of this study was to assess the association between adiposity and diabetes in four ethnic minority groups compared with Norwegians, and take into account confounding by socioeconomic position.MethodsData from questionnaires, physical examinations and serum samples were analysed for 30-to 60-year-olds from population-based cross-sectional surveys of Norwegians and four immigrant groups, comprising 4110 subjects born in Norway (n = 1871), Turkey (n = 387), Vietnam (n = 553), Sri Lanka (n = 879) and Pakistan (n = 420). Known and screening-detected diabetes cases were identified. The adiposity measures BMI, waist circumference and waist-hip ratio (WHR) were categorized into levels of adiposity. Gender-specific logistic regression models were applied to estimate the risk of diabetes for the ethnic minority groups adjusted for adiposity and income-generating work, years of education and body height used as a proxy for childhood socioeconomic position.ResultsThe age standardized diabetes prevalence differed significantly between the ethnic groups (women/men): Pakistan: 26.4% (95% CI 20.1-32.7)/20.0% (14.9-25.2); Sri Lanka: 22.5% (18.1-26.9)/20.7% (17.3-24.2), Turkey: 11.9% (7.2-16.7)/12.0% (7.6-16.4), Vietnam: 8.1% (5.1-11.2)/10.4% (6.6-14.1) and Norway: 2.7% (1.8-3.7)/6.4% (4.6-8.1). The prevalence increased more in the minority groups than in Norwegians with increasing levels of BMI, WHR and waist circumference, and most for women. Highly significant ethnic differences in the age-standardized prevalence of diabetes were found for both genders in all categories of all adiposity measures (p < 0.001). The Odds Ratio (OR) for diabetes adjusted for age, WHR, body height, education and income-generating work with Norwegians as reference was 2.9 (1.30-6.36) for Turkish, 2.7 (1.29-5.76) for Vietnamese, 8.0 (4.19-15.14) for Sri Lankan and 8.3 (4.37-15.58) for Pakistani women. Men from Sri Lanka and Pakistan had identical ORs (3.0 (1.80-5.12)).ConclusionsA high prevalence of diabetes was found in 30-to 60-year-olds from ethnic minority groups in Oslo, with those from Sri Lanka and Pakistan at highest risk. For all levels of adiposity, a higher susceptibility for diabetes was observed for ethnic minority groups compared with Norwegians. The association persisted after adjustment for socioeconomic position for all minority women and for men from Sri Lanka and Pakistan.

【 授权许可】

CC BY   
© Jenum et al; licensee BioMed Central Ltd. 2012