Epidemiology of childhood and adolescent cancer in Bangladesh, 2001–2014

BMC Cancer

Research Article

Shahinur Kabir¹  Salma Choudhury¹  Zohora Jameela Khan²  Md Mahmuduzzaman Mian³  Henrike E. Karim-Kos⁴  Humayun Kabir Sarker⁵  Mohammad Sorowar Hossain⁶  Sabina Karim⁷  Mamtaz Begum⁷  Asaduzzaman Khan⁸  Shameema Ferdous⁹ 

[1] ASHIC Foundation, Dhaka, Bangladesh;ASHIC Foundation, Dhaka, Bangladesh;Dhaka Medical College and Hospital, Dhaka, Bangladesh;Centre for Excellence, University of Dhaka, Dhaka, Bangladesh;Department of Public Health, Erasmus MC University Medical Centre, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands;Dhaka Medical College and Hospital, Dhaka, Bangladesh;Faculty of Basic Sciences, Bangladesh University of Health Sciences, Darus Salam, Mirpur-1, 1216, Dhaka, Bangladesh;National Institute of Cancer Research and Hospital, Dhaka, Bangladesh;School of Health and Rehabilitation Sciences, University of Queensland, Brisbane, Australia;Talent Hub, Banani, Dhaka, Bangladesh;

关键词: Bangladesh;    Cancer;    Childhood;    Adolescent;    Leukaemia;    ALL;    Retinoblastoma;    Incidence;   

DOI  :  10.1186/s12885-016-2161-0

 received in 2015-08-24, accepted in 2016-02-10,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundCancer burden among children and adolescents is largely unknown in Bangladesh. This study aims to provide a comprehensive overview on childhood and adolescent cancers and to contribute to the future strategies to deal with these diseases in Bangladesh.MethodsData on malignant neoplasms in patients aged less than 20 years diagnosed between 2001 and 2014 (N = 3143) in Bangladesh was collected by the National Institute of Cancer Research and Hospital and ASHIC Foundation. The age pattern and distribution of cancer types were analysed and the incidence rates were calculated.ResultsThe age-standardised incidence rate was 7.8 per million person-years for children (0–14 years) in the last time period (2011–2014). Retinoblastoma (25 %) and leukaemia (18 %) were the most common childhood cancers. For adolescents (15–19 years), the age-specific incidence rate was 2.1 per million person-years in the same time period. Most common adolescent cancers were malignant bone tumours (38 %), germ cell and gonadal tumours (17 %), and epithelial tumours (16 %). There were more boys affected (M: F ratio 2.0 in children and 1.4 in adolescents) than girls.ConclusionCancer incidences were lower than expected most likely due to a low level of awareness about cancer among clinicians and the population, inadequate access to health care, lack of diagnostic equipment and incomplete recording of cases. Improvements on different levels should be made to get a better epidemiologic insight and to detect cancer earlier resulting in a better outcome for affected children and adolescents.

【 授权许可】

CC BY   
© Hossain et al. 2016