期刊论文详细信息
BMC Public Health
An intervention to stop smoking among patients suspected of TB - evaluation of an integrated approach
Study Protocol
Amir Khan1  Maqsood Ahmad1  Kamran Siddiqi2 
[1] Association for Social Development, House No. 12, Street 48, F-7/4, Islamabad, Pakistan;Nuffield Centre for International Health and Development, Leeds Institute of Health Sciences, University of Leeds, Charles Thackrah Building, 101 Clarendon Road, LS2 9LJ, Woodhouse, Leeds, UK;
关键词: Nicotine;    Bupropion;    Nicotine Replacement Therapy;    Tobacco Control;    Tobacco Dependence;   
DOI  :  10.1186/1471-2458-10-160
 received in 2010-03-09, accepted in 2010-03-25,  发布年份 2010
来源: Springer
PDF
【 摘 要 】

BackgroundIn many low- and middle-income countries, where tobacco use is common, tuberculosis is also a major problem. Tobacco use increases the risk of developing tuberculosis, secondary mortality, poor treatment compliance and relapses. In countries with TB epidemic, even a modest relative risk leads to a significant attributable risk. Treating tobacco dependence, therefore, is likely to have benefits for controlling tuberculosis in addition to reducing the non-communicable disease burden associated with smoking. In poorly resourced health systems which face a dual burden of disease secondary to tuberculosis and tobacco, an integrated approach to tackle tobacco dependence in TB control could be economically desirable. During TB screening, health professionals come across large numbers of patients with respiratory symptoms, a significant proportion of which are likely to be tobacco users. These clinical encounters, considered to be "teachable moments", provide a window of opportunity to offer treatment for tobacco dependence.Methods/DesignWe aim to develop and trial a complex intervention to reduce tobacco dependence among TB suspects based on the WHO 'five steps to quit' model. This model relies on assessing personal motivation to quit tobacco use and uses it as the basis for assessing suitability for the different therapeutic options for tobacco dependence.We will use the Medical Research Council framework approach for evaluating complex interventions to: (a) design an evidence-based treatment package (likely to consist of training materials for health professionals and education tools for patients); (b) pilot the package to determine the delivery modalities in TB programme (c) assess the incremental cost-effectiveness of the package compared to usual care using a cluster RCT design; (d) to determine barriers and drivers to the provision of treatment of tobacco dependence within TB programmes; and (e) support long term implementation. The main outcomes to assess the effectiveness would be point abstinence at 4 weeks and continuous abstinence up to 6 months.DiscussionThis work will be carried out in Pakistan and is expected to have relevance for other low and middle income countries with high tobacco use and TB incidence. This will enhance our knowledge of the cost-effectiveness of treating tobacco dependence in patients suspected of TB.Trial RegistrationTrial Registration Number: ISRCTN08829879

【 授权许可】

CC BY   
© Siddiqi et al; licensee BioMed Central Ltd. 2010

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