Smart biomaterials - regulating cell behavior through signaling molecules

BMC Biology

Commentary

David L Kaplan¹  Aneta J Mieszawska¹ 

[1] Department of Biomedical Engineering, Tufts University, 4 Colby Street, 02155, Medford, MA, USA;

关键词: Vascular Endothelial Growth Factor;    Nerve Growth Factor;    Tissue Engineering;    PDMS;    Leukemia Inhibitory Factor;   

DOI  :  10.1186/1741-7007-8-59

 received in 2010-04-26, accepted in 2010-05-11,  发布年份 2010

来源: Springer

【 摘 要 】

Important advances in the field of tissue engineering are arising from increased interest in novel biomaterial designs with bioactive components that directly influence cell behavior. Following the recent work of Mitchell and co-workers published in BMC Biology, we review how spatial and temporal control of signaling molecules in a matrix material regulates cellular responses for tissue-specific applications.See research article http://www.biomedcentral.com/1741-7007/8/57

【 授权许可】

CC BY   
© Mieszawska and Kaplan; licensee BioMed Central Ltd. 2010