Folate intake and depressive symptoms in Japanese workers considering SES and job stress factors: J-HOPE study

BMC Psychiatry

Research Article

Hideki Hashimoto¹  Akiomi Inoue²  Akihito Shimazu³  Norito Kawakami³  Akizumi Tsutsumi⁴  Yixuan Song⁵  Koichi Miyaki⁵  Takuro Shimbo⁵  Nay Chi Htun⁶  Masaya Takahashi⁷  Sumiko Kurioka⁸ 

[1] Department of Health Economics and Epidemiology Research, School of Public Health, University of Tokyo, Tokyo, Japan;Department of Mental Health, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan;Department of Mental Health, Tokyo University Graduate School of Medicine, Tokyo, Japan;Department of public Health, Kitasato University School of Medecine, Sagamihara, Kanagawa, Japan;Division of Clinical Epidemiology, Department of Clinical Research and Informatics, National Center for Global Health and Medicine, Toyama 1-21-1, Shinjuku-ku, Tokyo, Japan;Division of Clinical Epidemiology, Department of Clinical Research and Informatics, National Center for Global Health and Medicine, Toyama 1-21-1, Shinjuku-ku, Tokyo, Japan;Department of Molecular Epidemiology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan;National Institute of Occupational Safety and Health, Kawasaki, Kanagawa, Japan;Occupational Health Training Center, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan;

关键词: Depressive Symptom;    Homocysteine;    Annual Household Income;    Folate Intake;    Dietary Folate Intake;   

DOI  :  10.1186/1471-244X-12-33

 received in 2011-10-11, accepted in 2012-03-29,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundRecently socioeconomic status (SES) and job stress index received more attention to affect mental health. Folate intake has been implicated to have negative association with depression. However, few studies were published for the evidence association together with the consideration of SES and job stress factors. The current study is a part of the Japanese study of Health, Occupation and Psychosocial factors related Equity (J-HOPE study) that focused on the association of social stratification and health and our objective was to clarify the association between folate intake and depressive symptoms in Japanese general workers.MethodsSubjects were 2266 workers in a Japanese nationwide company. SES and job stress factors were assessed by self-administered questionnaire. Folate intake was estimated by a validated, brief, self-administered diet history questionnaire. Depressive symptoms were measured by Kessler’s K6 questionnaire. “Individuals with depressive symptoms” was defined as K6≧9 (in K6 score of 0–24 scoring system). Multiple logistic regression and linear regression model were used to evaluate the association between folate and depressive symptoms.ResultsSeveral SES factors (proportion of management positions, years of continuous employment, and annual household income) and folate intake were found to be significantly lower in the subjects with depressive symptom (SES factors: p < 0.001; folate intake: P = 0.001). There was an inverse, independent linear association between K6 score and folate intake after adjusting for age, sex, job stress scores (job strains, worksite supports), and SES factors (p = 0.010). The impact of folate intake on the prevalence of depressive symptom by a multiple logistic model was (ORs[95% CI]: 0.813 [0.664-0.994]; P =0.044).ConclusionsOur cross-sectional study suggested an inverse, independent relation of energy-adjusted folate intake with depression score and prevalence of depressive symptoms in Japanese workers, together with the consideration of SES and job stress factors.

【 授权许可】

CC BY   
© Miyaki et al.; licensee BioMed Central Ltd. 2012