MELD score and antibiotics use are predictors of length of stay in patients hospitalized with hepatic encephalopathy

BMC Gastroenterology

Research Article

Douglas T Dieterich¹  Kian Bichoupan¹  Caitlin Homberger¹  Valérie Martel-Laferrière² 

[1] Department of Medicine, Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, 10029, New York, NY, USA;Department of Medicine, Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, 10029, New York, NY, USA;Département de microbiologie et maladies infectieuses et Centre de Recherche du Centre Hospitalier de l’Université de Montréal, 1058 St-Denis, H2X 3J4, Montréal, Qc, Canada;

关键词: Hepatic encephalopathy;    Length of stay;    MELD score;   

DOI  :  10.1186/1471-230X-14-185

 received in 2014-06-24, accepted in 2014-10-09,  发布年份 2014

来源: Springer

【 摘 要 】

BackgroundHepatic encephalopathy (HE) represents a significant burden to the healthcare system. The aim of this study was to determine factors influencing the hospital length of stay among patients hospitalized with HE.MethodsA data warehouse query was performed to identify 316 patients with a first hospitalization during which HE occurred, between April 2010 and February 2012. Baseline and hospitalization characteristics were collected with IRB approval. A negative binomial multivariable model was used to control for potential confounders on the length of hospitalization.ResultsMedian age was 59 years, and 60.4% of admitted patients were male. The median MELD score was 22 (IQR: 17-28). Median length of stay was 8 days (IQR: 3.25-14.25). After controlling for MELD score, female gender (2.2 days; p = 0.04), being initially admitted for a reason other than HE (liver-related: 7.6 days; p < 0.01 and non liver-related 10.7 days; p < 0.01) and receiving antibiotics other than rifaximin (10.5 days; p < 0.01) were associated with longer length of stay whereas hepatitis C (-3.1 days; p < 0.01) was associated with a shorter length of stay.ConclusionsMELD score, gender, use of antibiotics other than rifaximin, reason for admission and hepatitis C are predictors readily available in clinic that can help identify patients at risk for longer length of stay.

【 授权许可】

CC BY   
© Martel-Laferrière et al.; licensee BioMed Central Ltd. 2014