Atypical vitelliform macular dystrophy misdiagnosed as chronic central serous chorioretinopathy: case reports

BMC Ophthalmology

Case Report

Eung-Suk Kim¹  Young-Gyun Kim¹  Moosang Kim²  Young Seob Lee³  Hyung-Woo Kwak³  Seung-Young Yu³ 

[1] Department of Ophthalmology, School of Medicine, Eulji University, Daejeon, South Korea;Department of Ophthalmology, School of Medicine, Kangwon national University, Chuncheon, South Korea;Department of Ophthalmology, School of Medicine, Kyung Hee University, Seoul, South Korea;

关键词: Optical Coherence Tomography;    Photodynamic Therapy;    Fluorescein Angiography;    Polypoidal Choroidal Vasculopathy;    Central Serous Chorioretinopathy;   

DOI  :  10.1186/1471-2415-12-25

 received in 2011-11-26, accepted in 2012-07-06,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundTo report two cases of atypical vitelliform macular dystrophy misdiagnosed as chronic central serous chorioretinopathy.Case presentationTwo patients with incidentally discovered abnormalities of the retina without specific symptoms were referred to our hospital for consultation. Bilateral macula atrophic lesions were observed and optical coherence tomography revealed serous retinal detachment in the macula. Fluorescein angiography showed multiple leakages around the central hypofluorescent area and indocyanine green angiography showed partially dilated choroidal vessels. Fundus autofluorescence (FAF) showed a decreasing pattern of autofluorescence in the subretinal fluid area, and increasing autofluorescence at the border of the serous retinal detachment. Both patients were diagnosed with chronic central serous chorioretinopathy. Photodynamic therapy and intravitreal bevacizumab injection were administered for engorged choroidal vessels during follow-up, but neither patient showed improvement in symptoms or ophthalmologic findings. Based on re-evaluation by fundus photography, optical coherence tomography, fluorescein angiography, and comparison of the results of FAF with the first visit, vitelliform macular dystrophy was suspected and a definite diagnosis was made by electrooculography and genetic testing.ConclusionIn patients with continuous serous retinal detachment without response to photodynamic therapy or intravitreal bevacizumab injection, careful fundus exam and FAF can be used to diagnose atypical vitelliform macular dystrophy.

【 授权许可】

Unknown   
© Lee et al.; 2012. This article is published under license to BioMed Central Ltd. licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.