The DOMUS study protocol: a randomized clinical trial of accelerated transition from oncological treatment to specialized palliative care at home

BMC Palliative Care

Study Protocol

Annika Berglind von Heymann-Horan¹  Helle Timm²  Per Sjøgren³  Hans Von Der Maase⁴  Eva Soelberg Vadstrup⁴  Christoffer Johansen⁵  Mie Nordly⁶  Kirstine Skov Benthien⁶  Geana Paula Kurita⁷  Marie Kruse⁸ 

[1]Danish Cancer Society Research Center, Copenhagen, Denmark

[2]Danish Knowledge Centre for Palliative Care, Copenhagen, University of Southern Denmark, Copenhagen, Denmark

[3]Department of Clinical Medicine, Faculty of Health and Medical Sciences, Copenhagen University, Copenhagen, Denmark

[4]Section of Palliative Medicine, Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark

[5]Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, DK-2100, Copenhagen, Denmark

[6]Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, DK-2100, Copenhagen, Denmark

[7]Danish Cancer Society Research Center, Copenhagen, Denmark

[8]Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, DK-2100, Copenhagen, Denmark

[9]Department of Clinical Medicine, Faculty of Health and Medical Sciences, Copenhagen University, Copenhagen, Denmark

[10]Section of Palliative Medicine, Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark

[11]Multidisciplinary Pain Centre, Department of Neuroanaesthesiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark

[12]The Danish Institute for Local and Regional Research, Copenhagen, Denmark

关键词: Cancer;    Home care services;    Randomized controlled trial;    Specialized palliative care;    Palliative treatment;    Patient care;   

DOI  :  10.1186/1472-684X-13-44

 received in 2013-09-26, accepted in 2014-09-05,  发布年份 2014

来源: Springer

【 摘 要 】

BackgroundThe focus of Specialized Palliative Care (SPC) is to improve care for patients with incurable diseases and their families, which includes the opportunity to make their own choice of place of care and ultimately place of death.The Danish Palliative Care Trial (DOMUS) aims to investigate whether an accelerated transition process from oncological treatment to continuing SPC at home for patients with incurable cancer results in more patients reaching their preferred place of care and death. The SPC in this trial is enriched with a manualized psychological intervention.Methods/DesignDOMUS is a controlled randomized clinical trial with a balanced parallel-group randomization (1:1). The planned sample size is 340 in- and outpatients treated at the Department of Oncology at Copenhagen University Hospital. Patients are randomly assigned either to: a) standard care plus SPC enriched with a standardized psychological intervention for patients and caregivers at home or b) standard care alone. Inclusion criteria are incurable cancer with no or limited antineoplastic treatment options.DiscussionPrograms that facilitate transition from hospital treatment to SPC at home for patients with incurable cancer can be a powerful tool to improve patients’ quality of life and support family/caregivers during the disease trajectory. The present study offers a model for achieving optimal delivery of palliative care in the patient’s preferred place of care and attempt to clarify challenges.Trial registrationClinicaltrials.gov Identifier: NCT01885637

【 授权许可】

CC BY   
© Nordly et al.; licensee BioMed Central Ltd. 2014