Depressive mood mediates the influence of social support on health-related quality of life in elderly, multimorbid patients

BMC Family Practice

Research Article

Siegfried Weyerer¹  Jochen Gensichen²  Gerhard Schön³  Hans-Helmut König⁴  Martin Scherer⁵  Hendrik van den Bussche⁵  Heike Hansen⁵  Wolfgang Maier⁶  Horst Bickel⁷  Birgitt Wiese⁸  Karola Mergenthal⁹  Anne Dahlhaus⁹  Corina Güthlin⁹  Felix S Wicke⁹  Christin Löffler^1,10  Steffi G Riedel-Heller^1,11 

[1] Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany;Department of General Practice, Jena University Hospital, Jena, Germany;Department of Medical Biometry and Epidemiology, Hamburg-Eppendorf University Medical Center, Hamburg, Germany;Department of Medical Sociology and Health Economics, Hamburg Center for Health Economics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany;Department of Primary Medical Care, Hamburg-Eppendorf University Medical Center, Hamburg, Germany;Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany;Department of Psychiatry, Technical University of Munich, Munich, Germany;Institute for Biometry, Hannover Medical School, Hannover, Germany;Institute of General Practice, Goethe University Frankfurt, Frankfurt am Main, Germany;Institute of General Practice, Rostock University Medical Center, Rostock, Germany;Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig, Germany;

关键词: Multimorbidity;    Chronic medical conditions;    Coping;    Primary care;    Family practice;    Social support;    Health-related quality of life;    Depression;    Elderly patients;   

DOI  :  10.1186/1471-2296-15-62

 received in 2013-07-09, accepted in 2014-04-01,  发布年份 2014

来源: Springer

【 摘 要 】

BackgroundIt is not well established how psychosocial factors like social support and depression affect health-related quality of life in multimorbid and elderly patients. We investigated whether depressive mood mediates the influence of social support on health-related quality of life.MethodsCross-sectional data of 3,189 multimorbid patients from the baseline assessment of the German MultiCare cohort study were used. Mediation was tested using the approach described by Baron and Kenny based on multiple linear regression, and controlling for socioeconomic variables and burden of multimorbidity.ResultsMediation analyses confirmed that depressive mood mediates the influence of social support on health-related quality of life (Sobel’s p < 0.001). Multiple linear regression showed that the influence of depressive mood (β = −0.341, p < 0.01) on health-related quality of life is greater than the influence of multimorbidity (β = −0.234, p < 0.01).ConclusionSocial support influences health-related quality of life, but this association is strongly mediated by depressive mood. Depression should be taken into consideration in research on multimorbidity, and clinicians should be aware of its importance when caring for multimorbid patients.Trial registrationISRCTN89818205

【 授权许可】

Unknown   
© Wicke et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.