Primary malignant melanoma of the esophagus treated with subtotal esophagectomy: a case report

BMC Surgery

Case Report

Keisuke Okamura¹  Takehiro Noji¹  Takahiro Tsuchikawa¹  Yuma Ebihara¹  Soichi Murakami¹  Toru Nakamura¹  Yoshitsugu Nakanishi¹  Satoshi Hirano¹  Shota Kuwabara¹  Toshimichi Asano¹  Yo Kurashima¹  Toshiaki Shichinohe¹ 

[1] Department of Gastroenterological Surgery II, Hokkaido University Graduate School of Medicine, North 15 West 7, Kita-ku, 0608638, Sapporo, Hokkaido, Japan;

关键词: Esophagus;    Melanoma;    Pathology;    Treatment;    Prognosis;   

DOI  :  10.1186/s12893-017-0326-7

 received in 2017-08-09, accepted in 2017-11-21,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundPrimary malignant melanoma of the esophagus (PMME) is a rare disease with a poor prognosis. There are few reports of early-stage cases in which tumor invasion reached the lamina propria or muscularis mucosae, as in the present case. A standard treatment for early-stage PMME has not yet been established. The present study aimed to summarize previous reports and to discuss the indications for surgical treatment of early-stage primary malignant melanoma of the esophagus.Case presentationA 70-year-old woman with PMME was referred to our hospital. She underwent thoracoscopic and laparoscopic subtotal esophagectomy with lymphadenectomy. The resected specimen showed melanocytosis and junctional activity. Melanoma-specific antigens melan-A, S-100, and HMB45 were detected by immunohistochemical staining. The pathological diagnosis was pT1a-MM, pN0, pM0, and pStage IA. She remains alive without evidence of recurrence 39 months later.ConclusionSubtotal esophagectomy with regional radical lymphadenectomy could be recommended to patients with early-stage primary malignant melanoma of the esophagus, and curative surgical resection could improve their prognosis.

【 授权许可】

CC BY   
© The Author(s). 2017