Estimating view parameters from random projections for Tomography using spherical MDS

BMC Medical Imaging

Research Article

Yi Fang¹  Sundar Murugappan¹  Karthik Ramani² 

[1] School of Mechanical Engineering, Purdue University, West Lafayette, 47907, IN, USA;School of Mechanical Engineering, Purdue University, West Lafayette, 47907, IN, USA;School of Electrical Computer Engineering (by courtesy), Purdue University, 47907, West Lafayette, IN, USA;

关键词: Projection Data;    View Angle;    Random Projection;    High Dimensional Vector;    Embed Point;   

DOI  :  10.1186/1471-2342-10-12

 received in 2009-12-26, accepted in 2010-06-18,  发布年份 2010

来源: Springer

【 摘 要 】

BackgroundDuring the past decade, the computed tomography has been successfully applied to various fields especially in medicine. The estimation of view angles for projections is necessary in some special applications of tomography, for example, the structuring of viruses using electron microscopy and the compensation of the patient's motion over long scanning period.MethodsThis work introduces a novel approach, based on the spherical multidimensional scaling (sMDS), which transforms the problem of the angle estimation to a sphere constrained embedding problem. The proposed approach views each projection as a high dimensional vector with dimensionality equal to the number of sampling points on the projection. By using SMDS, then each projection vector is embedded onto a 1D sphere which parameterizes the projection with respect to view angles in a globally consistent manner. The parameterized projections are used for the final reconstruction of the image through the inverse radon transform. The entire reconstruction process is non-iterative and computationally efficient.ResultsThe effectiveness of the sMDS is verified with various experiments, including the evaluation of the reconstruction quality from different number of projections and resistance to different noise levels. The experimental results demonstrate the efficiency of the proposed method.ConclusionOur study provides an effective technique for the solution of 2D tomography with unknown acquisition view angles. The proposed method will be extended to three dimensional reconstructions in our future work. All materials, including source code and demos, are available on https://engineering.purdue.edu/PRECISE/SMDS.

【 授权许可】

CC BY   
© Fang et al; licensee BioMed Central Ltd. 2010