Elongator subunit 3 positively regulates plant immunity through its histone acetyltransferase and radical S-adenosylmethionine domains

BMC Plant Biology

Research Article

Zhonglin Mou¹  Yongsheng Wang¹  Christopher T DeFraia²  Jiqiang Yao³ 

[1] Department of Microbiology and Cell Science, University of Florida, 110700, 32611, Gainesville, FL, USA;Department of Microbiology and Cell Science, University of Florida, 110700, 32611, Gainesville, FL, USA;Department of Molecular Genetics, Ohio State University, 43210, Columbus, OH, USA;Interdisciplinary Center for Biotechnology Research, University of Florida, 103622, 32610, Gainesville, FL, USA;

关键词: Arabidopsis;    Elongator;    Plant immunity;    AtELP3;    Transcription;   

DOI  :  10.1186/1471-2229-13-102

 received in 2013-04-08, accepted in 2013-07-12,  发布年份 2013

来源: Springer

【 摘 要 】

BackgroundPathogen infection triggers a large-scale transcriptional reprogramming in plants, and the speed of this reprogramming affects the outcome of the infection. Our understanding of this process has significantly benefited from mutants that display either delayed or accelerated defense gene induction. In our previous work we demonstrated that the Arabidopsis Elongator complex subunit 2 (AtELP2) plays an important role in both basal immunity and effector-triggered immunity (ETI), and more recently showed that AtELP2 is involved in dynamic changes in histone acetylation and DNA methylation at several defense genes. However, the function of other Elongator subunits in plant immunity has not been characterized.ResultsIn the same genetic screen used to identify Atelp2, we found another Elongator mutant, Atelp3-10, which mimics Atelp2 in that it exhibits a delay in defense gene induction following salicylic acid treatment or pathogen infection. Similarly to AtELP2, AtELP3 is required for basal immunity and ETI, but not for systemic acquired resistance (SAR). Furthermore, we demonstrate that both the histone acetyltransferase and radical S-adenosylmethionine domains of AtELP3 are essential for its function in plant immunity.ConclusionOur results indicate that the entire Elongator complex is involved in basal immunity and ETI, but not in SAR, and support that Elongator may play a role in facilitating the transcriptional induction of defense genes through alterations to their chromatin.

【 授权许可】

Unknown   
© DeFraia et al.; licensee BioMed Central Ltd. 2013. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.