The Autism–Tics, ADHD and other Comorbidities inventory (A-TAC): previous and predictive validity

BMC Psychiatry

Research Article

Henrik Anckarsäter¹  Thomas Nilsson¹  Tomas Larson¹  Alessio Degl’Innocenti²  Caroline Mårland²  Sebastian Lundström³  Maria Råstam⁴  Paul Lichtenstein⁵  Christopher Gillberg⁶ 

[1] Centre for Ethics Law and Mental Health (CELAM) Institute of Neuroscience and Physiology, University of Gothenburg, SU Rättspsykiatri, Rågårdsvägen 5, Enhet CELAM Hus 1, SE-424 57 Gunnilse, Gothenburg, Sweden;Centre for Ethics Law and Mental Health (CELAM) Institute of Neuroscience and Physiology, University of Gothenburg, SU Rättspsykiatri, Rågårdsvägen 5, Enhet CELAM Hus 1, SE-424 57 Gunnilse, Gothenburg, Sweden;Department of Forensic Psychiatry, Sahlgrenska University Hospital, SU Rättspsykiatri, Rågårdsvägen 5, SE-424 57 Gunnilse, Gothenburg, Sweden;Centre for Ethics Law and Mental Health (CELAM) Institute of Neuroscience and Physiology, University of Gothenburg, SU Rättspsykiatri, Rågårdsvägen 5, Enhet CELAM Hus 1, SE-424 57 Gunnilse, Gothenburg, Sweden;Gillberg Neuropsychiatry Centre Institute of Neuroscience and Physiology, University of Gothenburg, Kungsgatan 12, SE-411 19, Göteborg, Sweden;Department of Clinical Sciences, Lund University, Box 117, SE-221 00, Lund, Sweden;Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, SE-171 77, Stockholm, Sweden;Gillberg Neuropsychiatry Centre Institute of Neuroscience and Physiology, University of Gothenburg, Kungsgatan 12, SE-411 19, Göteborg, Sweden;

关键词: Autism;    Neurodevelopmental disorders;    ADHD;    Screening;   

DOI  :  10.1186/s12888-017-1563-0

 received in 2016-12-21, accepted in 2017-11-30,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundReliable and easy to administer screening instruments focusing on neurodevelopmental disorders and associated conditions are scarce. The Autism–Tics, AD/HD and other Comorbidities inventory (A-TAC) has previously been validated and reporting good– excellent validity for several disorders. This article aims to expand these findings by including more conditions in a substantially larger sample augmented with the Swedish National Patient Register (NPR).MethodsSince 2004 parents of all 9-year-old Swedish twins have been invited to participate in a telephone interview in the Child and Adolescent Twin Study in Sweden, CATSS. The CATSS is linked to the NPR which includes data from in- and outpatient care. Data on neurodevelopmental disorders (A-TAC) collected in CATSS were compared with diagnoses from the NPR. We investigated diagnoses that had been made both before (previous validity) and after (predictive validity) the interview.ResultsSensitivity and specificity of A-TAC scores for predicting earlier or later clinical diagnoses were mostly good–excellent, with values of the area under the curve for a clinical diagnosis of autism spectrum disorder (ASD) of .98, attention deficit hyperactivity disorder (ADHD) .93, learning disorder (LD) .92, and oppositional defiant disorder (ODD) .99, with small differences in terms of previous and predictive analyses. A-TAC provided little validity for eating disorders.ConclusionThe result support previous claims: A-TAC is a broad screening instrument with a particular strength in assessing ASD, ADHD, LD, and ODD at ages 9 and 12, and also provides phenotypic information about other child psychiatric disorders.

【 授权许可】

CC BY   
© The Author(s). 2017