Association of blood glucose level and hypertension in Elderly Chinese Subjects: a community based study

BMC Endocrine Disorders

Research Article

Qun Yan¹  Bo Feng¹  Xu Li¹  Dongmei Sun²  Chenhong Gu³  Guoliang Chen³  Lun Li³  Qinghu Zheng³ 

[1] Department of Endocrinology, Shanghai East Hospital, Tongji University School of Medicine, 150 Jimo Road, 200120, Shanghai, China;Department of Endocrinology, Shanghai East Hospital, Tongji University School of Medicine, 150 Jimo Road, 200120, Shanghai, China;Puxing Community Health-Care Center, Pudong New District, 250 GuiChang Road, 200136, Shanghai, China;Puxing Community Health-Care Center, Pudong New District, 250 GuiChang Road, 200136, Shanghai, China;

关键词: Fasting plasma glucose;    Diabetes;    Hypertension;    Cross-sectional study;   

DOI  :  10.1186/s12902-016-0119-5

 received in 2016-02-22, accepted in 2016-06-22,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundThere is a scarcity of epidemiological researches examining the relationship between blood pressure (BP) and glucose level among older adults. The objective of the current study was to investigate the association of high BP and glucose level in elderly Chinese.MethodsA cross-sectional study of a population of 2092 Chinese individuals aged over 65 years was conducted. Multiple logistic analysis was used to explore the association between hypertension and hyperglycemia. Independent risk factors for systolic and diastolic BP were analyzed using stepwise linear regression.ResultsSubjects in impaired fasting glucose group (IFG) (n = 144) and diabetes (n = 346), as compared with normal fasting glucose (NFG) (n = 1277), had a significant higher risk for hypertension, with odds ratios (ORs) of 1.81 (95 % CI, 1.39–2.35) (P = 0.000) and 1.40 (95 % CI, 1.09–1.80) (P = 0.009), respectively. Higher fasting plasma glucose (FPG) levels in the normal range were still significantly associated with a higher prevalence of hypertension in both genders, with ORs of 1.24 (95 % CI, 0.85–1.80), R2 = 0.114, P = 0.023 in men and 1.61 (95 % CI, 1.12–2.30), R2 = 0.082, P = 0.010 in women, respectively, when compared with lower FPG. Linear regression analysis revealed FPG was an independent factor of systolic and diastolic BP.ConclusionsOur findings suggest that hyperglycemia as well as higher FPG within the normal range is associated with a higher prevalence of hypertension independent of other cardiovascular risk factors in elderly Chinese. Further studies are needed to explore the relationship between hyperglycemia and hypertension in a longitudinal setting.

【 授权许可】

CC BY   
© The Author(s). 2016