Body composition in males with adolescent idiopathic scoliosis: a case–control study with dual-energy X-ray absorptiometry

BMC Musculoskeletal Disorders

Research Article

Zezhang Zhu¹  Yong Qiu¹  Zhiwei Wang¹  Weijun Wang¹  Feng Zhu¹ 

[1] Spine Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Zhongshan Road 321, 210008, Nanjing, China;

关键词: Idiopathic scoliosis;    Body composition;    Lean mass;    Bone mineral content;    Body weight;   

DOI  :  10.1186/s12891-016-0968-0

 received in 2015-12-22, accepted in 2016-02-24,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundIn contrast to the well-characterized body growth and development of females with adolescent idiopathic scoliosis (AIS), the pubertal growth pattern of male patients has not been well-documented. Recently, significantly lower body weight (BW) and body mass index (BMI) were reported in males with AIS, and were thought to be related to curve progression. A case–control study was carried out to characterize the body composition and bone status of males with AIS, with the aim of gaining a better understanding of lower BW among these patients.MethodsForty-seven males with AIS and forty age- and gender-matched healthy controls were recruited. Standing height (SH) and BW were measured. The SH of the males who had AIS was corrected using Bjure’s equation, and then the BMI was calculated. Body composition, including subcranial fat mass (FM), lean mass (LM), and bone mineral content (BMC), and bone mineral density (BMD) were analyzed using dual-energy X-ray absorptiometry. The LM index (LMi) and the FM index (FMi) were calculated by dividing the FM and LM by the square of the SH. Logistic regression analysis was employed for comparison between AIS and controls.ResultsThe AIS patients had comparable age and Tanner staging for pubic hair as the controls. After adjustment for age, the AIS patients showed comparable SH but significantly lower BW and BMI than that of the controls. The LM, LMi, BMC and BMD were also significantly lower in the AIS patients than in the controls. However, the difference in BMC between two groups was not significant by adjusting for age, FM and LM.ConclusionThe male AIS patients showed abnormal body composition, presenting as significantly lower LM than the controls. The lower BMC observed in the patients might due to the abnormal body composition.

【 授权许可】

CC BY   
© Wang et al. 2016