Health related quality of life in patients with chronic gastritis and peptic ulcer and factors with impact: a longitudinal study

BMC Gastroenterology

Research Article

Julie Brunson¹  Qian Lu²  Zhengwei Wen³  Pingguang Lei³  Miao Zhao³  Chonghua Wan⁴  Jianfeng Tan⁴  Xiaomei Li⁵ 

[1] Department of Psychology, Pennsylvania State University, Pennsylvania, PA, USA;Department of Psychology, University of Houston, 77204, Houston, TX, USA;People’s Hospital of Songgang, Baoan, 518105, Shenzhen, Guangdong, China;School of Humanities and Management, Research Center for Quality of Life and Applied Psychology, Guangdong Medical College, 523808, Dongguan, China;School of Public Health, Kunming Medical University, 650031, Kunming, Yunnan, China;

关键词: Chronic digestive disease;    Health-related quality of life;    SF-36;    Influence factors;    Standardized response mean;   

DOI  :  10.1186/1471-230X-14-149

 received in 2013-03-31, accepted in 2014-08-12,  发布年份 2014

来源: Springer

【 摘 要 】

BackgroundThe assessment of Health Related Quality of Life (HRQOL) has been applied as a significant outcome indicator for patients with chronic diseases. No HRQOL study, however, has looked at HRQOL in patients with chronic gastritis and peptic ulcers. This paper focuses on comparing HRQOL in patients with chronic gastritis and peptic ulcers and examining the factors that influence the HRQOL of such patients. Results can be used for making decisions in clinical trials as well as aiding individual management and preventive care of these diseases.MethodsThe Chinese version of the SF-36 (CSF-36) was administered twice to 244 patients with chronic gastritis and peptic ulcers. Mean scores across the two disease groups were compared using t-tests, change over time was analyzed with paired samples t-tests, and factors predicting HRQOL were investigated using the univariate general linear model.ResultsThe mean domain scores of patients with chronic gastritis were lower than those for patients with peptic ulcers, with the exception of physical functioning. Both groups had lower HRQOL compared with population norms. Mean domain scores increased after treatment in both groups. HRQOL in patients with these two chronic diseases differed by age, education level, marriage, income, and gender, but their explanatory power was relatively low.ConclusionQuality of life of patients with chronic gastritis was lower than that of patients with peptic ulcers, which was lower than population norms. Quality of life in both patients groups was associated with socio-demographic risk factors.

【 授权许可】

Unknown   
© Wen et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.