A randomized, controlled clinical trial: the effect of mindfulness-based cognitive therapy on generalized anxiety disorder among Chinese community patients: protocol for a randomized trial

BMC Psychiatry

Study Protocol

Helen SW Ma¹  WK Tang²  Winnie WS Mak³  Herman HM Lo⁴  Rebecca LP Wong⁵  Samuel YS Wong⁵  Eliza YL Cheung⁵  Wacy WS Lui⁶  Candy YM Ling⁷  Stewart Mercer⁸ 

[1] Centre of Buddhist Studies, The University of Hong Kong, Hong Kong, China;Department of Psychiatry, The Chinese University of Hong Kong, Hong Kong, China;Department of Psychology, The Chinese University of Hong Kong, Hong Kong, China;Department of Social Work and Social Administration, The University of Hong Kong, Hong Kong, China;Division of Family Medicine and Primary Health Care, School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China;Hospital Authority, Hong Kong, China;New Life Psychiatric Rehabilitation Association, Hong Kong, China;Section of General Practice and Primary Care, University of Glasgow, Glasgow, UK;

关键词: Usual Care;    Anxiety Symptom;    Generalize Anxiety Disorder;    Usual Care Group;    Beck Anxiety Inventory;   

DOI  :  10.1186/1471-244X-11-187

 received in 2011-05-24, accepted in 2011-11-29,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundResearch suggests that an eight-week Mindfulness-Based Cognitive Therapy (MBCT) program may be effective in the treatment of generalized anxiety disorders. Our objective is to compare the clinical effectiveness of the MBCT program with a psycho-education programme and usual care in reducing anxiety symptoms in people suffering from generalized anxiety disorder.MethodsA three armed randomized, controlled clinical trial including 9-month post-treatment follow-up is proposed. Participants screened positive using the Structure Clinical Interview for DSM-IV (SCID) for general anxiety disorder will be recruited from community-based clinics. 228 participants will be randomly allocated to the MBCT program plus usual care, psycho-education program plus usual care or the usual care group. Validated Chinese version of instruments measuring anxiety and worry symptoms, depression, quality of life and health service utilization will be used. Our primary end point is the change of anxiety and worry score (Beck Anxiety Inventory and Penn State Worry Scale) from baseline to the end of intervention. For primary analyses, treatment outcomes will be assessed by ANCOVA, with change in anxiety score as the baseline variable, while the baseline anxiety score and other baseline characteristics that significantly differ between groups will serve as covariates.ConclusionsThis is a first randomized controlled trial that compare the effectiveness of MBCT with an active control, findings will advance current knowledge in the management of GAD and the way that group intervention can be delivered and inform future research.Unique Trail Number (assigned by Centre for Clinical Trails, Clinical Trials registry, The Chinese University of Hong Kong): CUHK_CCT00267

【 授权许可】

CC BY   
© Wong et al; licensee BioMed Central Ltd. 2011