Fluoride bioavailability in saliva and plaque

BMC Oral Health

Research Article

Phillip Kuehnl¹  Ljubisa Markovic¹  Ella A Naumova¹  Wolfgang H Arnold¹  Peter Gaengler¹  Philipp Hertenstein¹  Rainer A Jordan¹ 

[1] Faculty of Health, Department of Dentistry, University of Witten/Herdecke, Alfred Herrhausenstrasse 50, 58448, Witten, Germany;

关键词: Fluoride;    Fluoride Concentration;    Dental Plaque;    Enamel Surface;    Tooth Brushing;   

DOI  :  10.1186/1472-6831-12-3

 received in 2010-11-22, accepted in 2012-01-09,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundDifferent fluoride formulations may have different effects on caries prevention. It was the aim of this clinical study to assess the fluoride content, provided by NaF compared to amine fluoride, in saliva and plaque.MethodsEight trained volunteers brushed their teeth in the morning for 3 minutes with either NaF or amine fluoride, and saliva and 3-day-plaque-regrowth was collected at 5 time intervals during 6 hours after tooth brushing. The amount of collected saliva and plaque was measured, and the fluoride content was analysed using a fluoride sensitive electrode. All subjects repeated all study cycles 5 times, and 3 cycles per subject underwent statistical analysis using the Wilcoxon-Mann-Whitney test.ResultsImmediately after brushing the fluoride concentration in saliva increased rapidly and dropped to the baseline level after 360 minutes. No difference was found between NaF and amine fluoride. All plaque fluoride levels were elevated after 30 minutes until 120 minutes after tooth brushing, and decreasing after 360 minutes to baseline. According to the highly individual profile of fluoride in saliva and plaque, both levels of bioavailability correlated for the first 30 minutes, and the fluoride content of saliva and plaque was back to baseline after 6 hours.ConclusionsFluoride levels in saliva and plaque are interindividually highly variable. However, no significant difference in bioavailability between NaF and amine fluoride, in saliva, or in plaque was found.

【 授权许可】

Unknown   
© Naumova et al; licensee BioMed Central Ltd. 2012. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.