Association between serum 25-hidroxyvitamin D concentrations and ultraviolet index in Portuguese older adults: a cross-sectional study

BMC Geriatrics

Research Article

Cláudia Afonso¹  Ana S. Sousa¹  Sofia Cardoso¹  Nuno Borges²  Pedro Moreira³  Patrícia Padrão⁴  Alejandro Santos⁵  Rita S. Guerra⁶  Teresa F. Amaral⁶ 

[1] Faculdade de Ciências da Nutrição e Alimentação da Universidade do Porto Rua Dr. Roberto Frias, 4200-465, Porto, Portugal;Faculdade de Ciências da Nutrição e Alimentação da Universidade do Porto Rua Dr. Roberto Frias, 4200-465, Porto, Portugal;CINTESIS - Centre for Health Technology and Services Research, Rua Dr. Plácido da Costa, 4200-450, Porto, Portugal;Faculdade de Ciências da Nutrição e Alimentação da Universidade do Porto Rua Dr. Roberto Frias, 4200-465, Porto, Portugal;Centro de Investigação em Atividade Física, Saúde e Lazer, Universidade do Porto, R. Dr. Plácido da Costa 91, 4200-450, Porto, Portugal;CINTESIS - Centre for Health Technology and Services Research, Rua Dr. Plácido da Costa, 4200-450, Porto, Portugal;Faculdade de Ciências da Nutrição e Alimentação da Universidade do Porto Rua Dr. Roberto Frias, 4200-465, Porto, Portugal;EPIUnit, Instituto de Saúde Pública, Universidade do Porto, Rua das Taipas, n° 135, 4050-600, Porto, Portugal;Faculdade de Ciências da Nutrição e Alimentação da Universidade do Porto Rua Dr. Roberto Frias, 4200-465, Porto, Portugal;I3S-Instituto de Investigação e Inovação em Saúde, R. Alfredo Allen, 4200-135, Porto, Portugal;Faculdade de Ciências da Nutrição e Alimentação da Universidade do Porto Rua Dr. Roberto Frias, 4200-465, Porto, Portugal;UISPA, LAETA-INEGI, Faculdade de Engenharia, Universidade do Porto, Porto, Portugal;

关键词: Vitamin D;    Vitamin D deficiency;    Older adults;    Cutaneous synthesis;    25-hydroxyvitamin D3;    Ultraviolet index;   

DOI  :  10.1186/s12877-017-0644-8

 received in 2017-04-21, accepted in 2017-10-16,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundThe older population is a risk group for hypovitaminosis D. The Ultraviolet Index (UVI) can be an indicator of potential for cutaneous synthesis of vitamin D but physiological and other environmental factors also influence vitamin D synthesis and status. Knowledge about vitamin D status in Portuguese older adults is limited. This study aims to explore the association between Ultraviolet Index and serum 25-hidroxyvitamin D3 [25(OH)D] levels accounting for other potential influential factors.MethodsA cross-sectional study was conducted between December 2015 and June 2016, in 1497 Portuguese older adults (≥ 65 years) within Nutrition UP 65 project. For each participant, serum 25(OH)D was determined and the mean UVI (mUVI) in the respective residence district was calculated for the previous 30 days. Stepwise linear regression analyses were conducted for the following periods of blood collection: between December and June, December and March and April and June. Standardized regression coefficients (Sβ) and 95% confidence intervals were calculated.ResultsThe median 25(OH)D concentration was 35.9 nmol/L. The UVI was independently and positively associated with 25(OH)D in the models for December–June (Sβ = 0.244, 95% CI: 0.198; 0.291, P < 0.001) and April–June (Sβ = 0.295, 95% CI: 0.299; 0.362, P < 0.001) and independently and negatively associated in December–March period (Sβ = −0.149, 95% CI: -0.211; −0.087, P < 0.001).ConclusionsIn this sample with high vitamin D deficiency frequency, the UVI was a predictor of 25(OH)D levels but the direction of the association varied according to the blood collection period. Our results suggest that accounting for the time of year in future research regarding vitamin status and related public health recommendations may be relevant.

【 授权许可】

CC BY   
© The Author(s). 2017