Outcome of Phacoemulsification in patients with and without Pseudoexfoliation syndrome in Kashmir

BMC Ophthalmology

Research Article

Aalia R Sufi¹  Tejit Singh¹  Mudassar H Rather²  Asmat Ara Mufti³ 

[1] Department of Ophthalmology, Government Medical College, Jammu & Kashmir, Srinagar, India;Department of Surgery, Government Medical College, Jammu & Kashmir, Srinagar, India;Directorate of Health Services, Kashmir, India;

关键词: Visual Acuity;    Corneal Edema;    Pseudoexfoliation Syndrome;    Vitreous Loss;    Anterior Lens Capsule;   

DOI  :  10.1186/1471-2415-12-13

 received in 2011-09-14, accepted in 2012-05-18,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundThe aim of the study is to compare the outcome of phacoemulsification in patients with and without pseudoexfoliation syndrome in Kashmir.Methods200 patients were prospectively evaluated and divided into 2 groups. Group 1 comprised 100 cases with pseudoexfoliation and Group 2 (control) 100 cases without pseudoexfoliation. Phacoemulsification with posterior chamber intraocular lens implantation was performed by 3 surgeons. Intraoperative and postoperative observations were made in both the groups at regular intervals upto 6 months. A chi square test was used for statistical analysis.ResultsPatients with pseudoexfoliation were significantly older (P = 0.000), had harder cataract(P = 0.030) and smaller mean pupil diameter(P = 0.000) than the control group. Intraoperative complications were comparable between the 2 groups except the occurrence of zonular dehiscence which was seen in 7% patients of Group 1 compared to 0% in Group 2. Higher postoperative inflammatory response was seen in Group 1(P = 0.000). Decrease in intraocular pressure (IOP) at all postoperative measurements was more in Group 1(P = 0.000). The visual acuity was better in the control group in the early postoperative period (P = 0.029), however the final visual acuity at 6 months was comparable between the 2 groups.ConclusionsPhacoemulsification in presence of pseudoexfoliation necessitates appropriate surgical technique to avoid intraoperative complications. Pseudoexfoliation is associated with higher inflammatory response, significant postoperative IOP drop and satisfactory visual outcome.

【 授权许可】

CC BY   
© Sufi et al.; licensee BioMed Central Ltd. 2012