Profiling intraoral neuropathic disturbances following lingual nerve injury and in burning mouth syndrome

BMC Oral Health

Research Article

Monika Daubländer¹  Claudia Welte-Jzyk¹  Roman Rolke²  Malte Bittner³  Amely Hartmann⁴  Robin Seeberger⁵ 

[1] Department of Oral Surgery, University Medical Centre of the Johannes Gutenberg University of Mainz, Mainz, Germany;Department of Palliative Medicine, University of Aachen, Aachen, Germany;Private Practice Dr. Meschenmoser und Dr. Bittner, Stuttgart, Germany;Private Practice Dr. Seiler und Kollegen, Echterdinger Str. 7, 70794, Filderstadt, Germany;Private Practice MKG Solitude, Ludwigsburg, Germany;

关键词: Lingual nerve impairment;    Quantitative Sensory Testing;    Burning mouth syndrome;    Neurosensory disturbances;   

DOI  :  10.1186/s12903-017-0360-y

 received in 2016-07-27, accepted in 2017-03-08,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundThe aim of the study was to analyse intraoral neurophysiological changes in patients with unilateral lingual nerve lesions as well as patients with Burning Mouth Syndrome (BMS) by applying a standardized Quantitative Sensory Testing (QST) protocol.MethodsThe study included patients suffering from a peripheral lesion of the lingual nerve (n = 4), from BMS (n = 5) and healthy controls (n = 8). Neurophysiological tests were performed in the innervation areas of the tongue bilaterally. For BMS patients the dorsal foot area was used as reference.ResultsFor patients with peripheral lesion of the lingual nerve the affected side of the tongue showed increased thresholds for thermal (p < 0.05–0.001) and mechanical (p < 0.01–0.001) QST parameters, indicating a hypoesthesia and thermal hypofunction. In BMS patients, a pinprick hypoalgesia (p < 0.001), a cold hyperalgesia (p < 0.01) and cold/warmth hypoesthesia (p < 0.01) could be detected.ConclusionsThe results of this study verified the lingual nerve lesion in our patients as a peripheral dysfunction. The profile showed a loss of sensory function for small and large fibre mediated stimuli. A more differentiated classification of the lingual nerve injury was possible with QST, regarding profile, type and severity of the neurologic lesion. BMS could be seen as neuropathy with variable central and peripheral contributions among individuals resulting in chronic pain.

【 授权许可】

CC BY   
© The Author(s). 2017