The Scandinavian Solutions for Wellness study - a two-arm observational study on the effectiveness of lifestyle intervention on subjective well-being and weight among persons with psychiatric disorders

BMC Psychiatry

Research Article

Eva Lindström¹  Egil W Martinsen²  Pär Svanborg³  Vibeke Porsdal⁴  Ole Kristian Kleivenes⁵  Harriet Nilsson⁶  Catherine Beal⁷ 

[1] Clinic of forensic psychiatry, Malmö University Hospital, Malmö, Sweden;Clinic of psychiatric health, Aker University Hospital, Oslo, Norway;Dept of Clinical Neuroscience, Eli Lilly Sweden AB, Karolinska Institutet, Stockholm, Sweden;Eli Lilly Danmark A/S, Nybrovej 110, DK - 2800, Lyngby, Denmark;Eli Lilly Norge A.S, P.O. box 6090, Grenseveien 99, N-0601, Oslo, Etterstad, Norway;ICON Clinical Research Limited, Gårdsvägen 18, SE-169 27, Solna, Sweden;Keyrus BioPharma, 53, rue Baudin, F-92300, Levallois-Perret, France;

关键词: Schizophrenia;    Waist Circumference;    Psychotropic Medication;    Control Group Participant;    Single Index Score;   

DOI  :  10.1186/1471-244X-10-42

 received in 2009-11-23, accepted in 2010-06-10,  发布年份 2010

来源: Springer

【 摘 要 】

BackgroundSolutions for Wellness (SfW) is an educational 3-month program concerning nutrition and exercise for persons with psychiatric disorders on psychotropic medication, who have weight problems. This observational study assessed the impact of SfW on subjective well-being, weight and waist circumference (WC).MethodsData was collected at 49 psychiatric clinics. Where the SfW program was offered patients could enter the intervention group; where not, the control group. Subjective well-being was measured by the Subjective Well-being under Neuroleptics scale (SWN), at baseline, at the end of SfW participation, and at a follow-up 6 months after baseline. Demographic, disease and treatment data was also collected.Results314 patients enrolled in the SfW group, 59 in the control group. 54% of the patients had schizophrenia, 67% received atypical antipsychotics, 56% were female. They averaged 41 ± 12.06 years and had a BMI of 31.4 ± 6.35. There were significant differences at baseline between groups for weight, SWN total score and other factors. Stepwise logistic models controlling for baseline covariates yielded an adjusted non-significant association between SfW program participation and response in subjective well-being (SWN increase). However, statistically significant associations were found between program participation and weight-response (weight loss or gain < 1 kg) OR = 2; 95% CI [1.1; 3.7] and between program participation and WC-response (WC decrease or increase < 2 cm) OR = 5; 95% CI [2.4; 10.3]), at 3 months after baseline.ConclusionsSfW program participation was associated with maintaining or decreasing weight and WC but not with improved subjective well-being as measured with the SWN scale.

【 授权许可】

CC BY   
© Porsdal et al; licensee BioMed Central Ltd. 2010