A long-surviving patient with advanced esophageal basaloid squamous cell carcinoma treated only with radiotherapy: case report and literature review

BMC Gastroenterology

Case Report

Moritaka Ohhara¹  Homma Taku²  Toshirou Takimoto³  Yoshiaki Tanaka⁴  Toshiya Maebayashi⁵  Naoya Ishibashi⁵  Takuya Aizawa⁵  Masakuni Sakaguchi⁵ 

[1]Department of Digestive Surgery, Kasukabe Medical Center, Kasukabe, 344-8588, Saitama, Japan

[2]Department of Human Pathology, Division of Pathology and Microbiology, Nihion University School of Medicine, Itabashi-ku, 173-8610, Tokyo, Japan

[3]Department of Pathology, Kasukabe Medical Center, Kasukabe, 344-8588, Saitama, Japan

[4]Department of Radiation Oncology, Kawasaki Saiwai Hospital, 212-0014, Kawasaki, Kanagawa, Japan

[5]Department of Radiology, Nihon University School of Medicine, 30-1 Oyaguchi Kami-cho, Itabashi-ku, 173-8610, Tokyo, Japan

关键词: Esophageal basaloid squamous cell carcinoma;    Radiation therapy;   

DOI  :  10.1186/s12876-017-0714-6

 received in 2017-06-09, accepted in 2017-11-27,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundEsophageal basaloid squamous cell carcinoma (EBSCC) is a rare malignant disease. Advanced EBSCC (AEBSCC) has a poorer prognosis than the more common esophageal squamous cell carcinoma, but no treatment policy has yet been established. This is the first reported case with AEBSCC treated only with radiotherapy. Thus, our long-surviving patient merits consideration. We therefore reviewed cases with the same stage of AEBSCC for further investigation.Case presentationAn 85-year-old man with a chief complaint of difficulty swallowing foods was diagnosed with AEBSCC, cT3N1M0, stage III, by thorough examination. The basaloid carcinoma extended from the upper thoracic esophagus to the middle thoracic esophagus based on imaging studies, endoscopy and biopsy.Morphologically, the tumor was an elevated ulcerative area. We conducted radiotherapy to relieve symptoms, as the patient and his family refused aggressive treatment. He has remained alive without recurrence for 2 years, to date, after completing radiotherapy.ConclusionsBasaloid carcinoma might be highly sensitive to radiotherapy. Thus, radiotherapy for local control might be beneficial for elderly patients with complications and those refusing aggressive treatment.

【 授权许可】

CC BY   
© The Author(s). 2017