Symptom clusters and related factors in bladder cancer patients three months after radical cystectomy

BMC Urology

Research Article

Ping Tang¹  Qinghua Zhao²  Hongyan Ren³  Guosheng Ren⁴ 

[1] Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, 400016, Chongqing, China;Department of Nursing, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, 400016, Chongqing, China;Department of Urology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, 400016, Chongqing, China;Molecular Oncology and Epigenetics Laboratory, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, 400016, Chongqing, China;

关键词: Bladder cancer;    Quality of life;    Radical cystectomy;    Symptom cluster;    Symptom distress;   

DOI  :  10.1186/s12894-017-0255-x

 received in 2016-09-30, accepted in 2017-08-11,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundTo identify symptom distress and clusters in patients 3 months after radical cystectomy and to explore their potential predictors.MethodsA cross-sectional design was used to investigate 99 bladder cancer patients 3 months after radical cystectomy. Data were collected by demographic and disease characteristic questionnaires, the symptom experience scale of the M.D. Anderson symptom inventory, two additional symptoms specific to radical cystectomy, and the functional assessment of cancer therapy questionnaire. A factor analysis, stepwise regression, and correlation analysis were applied.ResultsThree symptom clusters were identified: fatigue-malaise, gastrointestinal, and psycho-urinary. Age, complication severity, albumin post-surgery (negative), orthotropic neobladder reconstruction, adjuvant chemotherapy and American Society of Anesthesiologists (ASA) scores were significant predictors of fatigue-malaise. Adjuvant chemotherapy, orthotropic neobladder reconstruction, female gender, ASA scores and albumin (negative) were significant predictors of gastrointestinal symptoms. Being unmarried, having a higher educational level and complication severity were significant predictors of psycho-urinary symptoms. The correlations between clusters and for each cluster with quality of life were significant, with the highest correlation observed between the psycho-urinary cluster and quality of life.ConclusionsBladder cancer patients experience concurrent symptoms that appear to cluster and are significantly correlated with quality of life. Moreover, symptom clusters may be predicted by certain demographic and clinical characteristics.

【 授权许可】

CC BY   
© The Author(s). 2017