Effectiveness of acupuncture for angina pectoris: a systematic review of randomized controlled trials

BMC Complementary and Alternative Medicine

Research Article

Zhe Zhang¹  Huijuan Cao²  Ying Wang³  Changhe Yu⁴  Kangshou Ji⁴  Guanlin Yang⁵  Hwang Hye Jin⁶ 

[1] Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, China;Center for Evidence-Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China;Center of Education and Laboratory, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, China;First Clinical Department, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, China;Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, China;Oriental medical college, Kyung Hee University, Dongdaemun-gu, Korea;

关键词: Acupuncture;    Angina pectoris;    Systematic review;    Randomized controlled trial;    Meta-analysis;   

DOI  :  10.1186/s12906-015-0586-7

 received in 2013-04-05, accepted in 2015-02-25,  发布年份 2015

来源: Springer

【 摘 要 】

BackgroundThe purpose of this systematic review is to assess the effectiveness of acupuncture for angina pectoris.MethodsEleven electronic databases were searched until January 2013. The study included randomized controlled trials that the effectiveness of acupuncture alone was compared to anti-angina medicines (in addition to conventional treatment) and the effectiveness of a combination of acupuncture plus anti-angina medicines was compared to anti-angina medicines alone. The trial selection, data extraction, quality assessment and data analytic procedures outlined in the 2011 Cochrane Handbook were involved.ResultsThe study included 25 randomized controlled trials (involving 2,058 patients) that met our inclusion criteria. The pooled results showed that the number of patients with ineffectiveness of angina relief was less in the combined acupuncture-anti-angina treatment group than in the anti-angina medicines alone group (RR 0.33, 95% CI 0.23-0.47, p < 0.00001, I2 = 0%). Similarly, compared to the anti-angina medicines alone group, fewer patients in the combined treatment group showed no ECG improvement (RR 0.50, 95% CI 0.40-0.62, p < 0.00001, I2 = 0%). However, no differences were observed between acupuncture treatment alone and anti-angina medicines alone for both outcome measures. Only four trials mentioned adverse effects. One trial found no significant difference between acupuncture and Chinese medicine, and three reported no adverse events. The quality of the trials was found to be low.ConclusionsThe findings showed very low evidence to support the use of acupuncture for improving angina symptoms and ECG of angina patients. However, the quality of the trials included in this study was low. Large and rigorously designed trials are needed to confirm the potential benefit and adverse events of acupuncture.

【 授权许可】

Unknown   
© Yu et al.; licensee BioMed Central. 2015. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.