Co-morbidity of personality disorder in schizophrenia among psychiatric outpatients in China: data from epidemiologic survey in a clinical population

BMC Psychiatry

Research Article

Yi Cui¹  Tong Su¹  ZiQiang Li¹  Xiao Pan¹  YunXiang Tang¹  YanYan Wei²  Annabelle Chow³  LiHua Xu⁴  TianHong Zhang⁴  KaiDa Jiang⁴  XiaoHua Liu⁴  YingYing Tang⁴  ZePing Xiao⁴  YunFei Dai⁴  JiJun Wang⁵ 

[1] Department of Medical Psychology, Faculty of Mental Health, Second Military Medical University, 200433, Shanghai, People’s Republic of China;Department of Medical Psychology, Faculty of Mental Health, Second Military Medical University, 200433, Shanghai, People’s Republic of China;Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, 600 South Wanping Road, 200030, Shanghai, People’s Republic of China;Department of Psychological Medicine, Changi General Hospital, Singapore, Singapore;Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, 600 South Wanping Road, 200030, Shanghai, People’s Republic of China;Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, 600 South Wanping Road, 200030, Shanghai, People’s Republic of China;Shanghai Key Laboratory of Psychotic Disorders (No.13dz2260500), Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai, People’s Republic of China;

关键词: Schizotypal personality disorder;    Prevalence;    Cluster-A personality disorders;    Psychosis;    Clinical population;   

DOI  :  10.1186/s12888-016-0920-8

 received in 2015-07-05, accepted in 2016-06-22,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundThe reported rates of personality disorder (PD) in subjects with schizophrenia (SZ) are quite varied across different countries, and less is known about the heterogeneity of PD among subjects with SZ. We examined the co-morbidity of PD among patients who are in the stable phase of SZ.Method850 subjects were randomly sampled from patients diagnosed with SZ in psychiatric and psycho-counseling clinics at Shanghai Mental Health Center. Co-morbidity of PDs was assessed through preliminary screening and patients were administered several modules of the SCID-II. Evidence of heterogeneity was evaluated by comparing patients diagnosed with SZ with those who presented with either affective disorder or neurosis (ADN).Results204 outpatients (24.0 %) in the stable phase of SZ met criteria for at least one type of DSM-IV PD. There was a higher prevalence of Cluster-A (odd and eccentric PD) and C (anxious and panic PD) PDs in SZ (around 12.0 %). The most prevalent PD was the paranoid subtype (7.65 %). Subjects with SZ were significantly more likely to have schizotypal PD (4.4 % vs. 2.1 %, p = 0.003) and paranoid PD (7.6 % vs. 5.4 %, p = 0.034), but much less likely to have borderline, obsessive-compulsive, depressive, narcissistic and histrionic PD.ConclusionsThese findings suggest that DSM-IV PD is common in patients with SZ than in the general population. Patterns of co-morbidity with PDs in SZ are different from ADN.

【 授权许可】

CC BY   
© The Author(s). 2016