Moxibustion for ulcerative colitis: a systematic review and meta-analysis

BMC Gastroenterology

Research Article

Edzard Ernst¹  Jong-In Kim²  Sun-Mi Choi³  Tae-Young Choi³  Dong-Hyo Lee⁴  Myeong Soo Lee⁵ 

[1] Complementary Medicine, Peninsula Medical School, Universities of Exeter & Plymouth, Exeter, UK;Department of Acupuncture and Moxibustion, College of Oriental Medicine, Kyung Hee University Medical Center, Seoul, Korea;Division of Standard Research, Korea Institute of Oriental Medicine, Daejeon, Korea;Division of Standard Research, Korea Institute of Oriental Medicine, Daejeon, Korea;Clinical Research Center, Wonkwang University Sanbon Oriental Medical Center, Gunpo, Korea;Division of Standard Research, Korea Institute of Oriental Medicine, Daejeon, Korea;Complementary Medicine, Peninsula Medical School, Universities of Exeter & Plymouth, Exeter, UK;

关键词: Ulcerative Colitis;    Sulfasalazine;    Acupuncture Point;    Moxibustion Group;    Parallel Group Design;   

DOI  :  10.1186/1471-230X-10-36

 received in 2009-10-07, accepted in 2010-04-07,  发布年份 2010

来源: Springer

【 摘 要 】

BackgroundComplementary and alternative medicine (CAM) is increasingly used for treatment of inflammatory bowel disease (IBD). Acupuncture-type treatments are among the most popular options. Several studies have reported that moxibustion is effective in ulcerative colitis (UC). The objective of this review was to assess the clinical evidence for or against moxibustion as a treatment for UC.MethodsWe searched the literature using 18 databases from their inception to February 10, 2010, without language restrictions. We included randomized clinical trials (RCTs), in which human patients with UC were treated with moxibustion. Studies were included if they were placebo-controlled or controlled against a drug therapy or no treatment group. The methodological quality of all RCTs was assessed using the Cochrane risk of bias.ResultsIn total, five RCTs were included. All were of low methodological quality. They compared the effects of moxibustion with conventional drug therapy. Three tested moxibustion against sulfasalazine and two against sulfasalazine plus other drugs. A meta-analysis of five RCTs showed favorable effects of moxibustion on the response rate compared to conventional drug therapy (n = 407; risk ratio = 1.24, 95% CI = 1.11 to 1.38; P < 0.0001; heterogeneity: I2 = 16%).ConclusionsCurrent evidence is insufficient to show that moxibustion is an effective treatment of UC. Most of included trials had high risk of bias. More rigorous studies seem warranted.

【 授权许可】

CC BY   
© Lee et al; licensee BioMed Central Ltd. 2010