A Chinese patient with peritoneal dialysis-related peritonitis caused by Gordonia terrae: a case report

BMC Infectious Diseases

Case Report

Chenrui Hou¹  Yun Yang¹  Ziyang Li¹ 

[1]Department of Clinical Laboratory, The Shanxi Dayi Hospital, 99 Longcheng Road, 030032, Taiyuan, Shanxi, China

关键词: Peritonitis;    Peritoneal dialysis;    Gordonia terrae;    Case report;   

DOI  :  10.1186/s12879-017-2283-2

 received in 2016-11-17, accepted in 2017-02-22,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundGordonia terrae is a rare cause of clinical infections, with only 23 reported cases. We report the first case of peritoneal dialysis-related peritonitis caused by Gordonia terrae in mainland China.Case presentationA 52-year-old man developed peritoneal dialysis-related peritonitis and received preliminary antibiotic treatment. After claiming that his symptoms had been resolved, the patient insisted on being discharged (despite our recommendations) and did not receive continued treatment after leaving the hospital. A telephone follow-up with the patient’s relatives revealed that the patient died 3 months later. Routine testing did not identify the bacterial strain responsible for the infection, although matrix-assisted laser desorption/ionization time-of-flight mass spectrometry identified the strain as Gordonia rubropertincta. However, a 16S rRNA sequence analysis using an isolate from the peritoneal fluid culture revealed that the responsible strain was actually Gordonia terrae. Similar to this case, all previously reported cases have involved a delayed diagnosis and initial treatment failure, and the definitive diagnosis required a 16S rRNA sequence analysis. Changes from an inappropriate antibiotic therapy to an appropriate one have relied on microbiological testing and were performed 7–32 days after the initial treatment.ConclusionsThe findings from our case and the previously reported cases indicate that peritoneal dialysis-related peritonitis caused by Gordonia terrae can be difficult to identify and treat. It may be especially challenging to diagnose these cases in countries with limited diagnostic resources.

【 授权许可】

CC BY   
© The Author(s). 2017