Small average differences in attenuation corrected images between men and women in myocardial perfusion scintigraphy: a novel normal stress database

BMC Medical Imaging

Research Article

Elin Trägårdh¹  Lars Edenbrandt¹  David Jakobsson¹  Karl Sjöstrand² 

[1] Clinical Physiology and Nuclear Medicine Unit, Skåne University Hospital, Lund University, Malmö, Sweden;Informatics and Mathematical Modeling, Technical University of Denmark, Copenhagen, Denmark;

关键词: Attenuation Correct;    Nuclear Cardiology;    Myocardial Perfusion Scintigraphy;    Normal Database;    Attenuation Correct Method;   

DOI  :  10.1186/1471-2342-11-18

 received in 2011-02-28, accepted in 2011-10-03,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundThe American Society of Nuclear Cardiology and the Society of Nuclear Medicine state that incorporation of attenuation-corrected (AC) images in myocardial perfusion scintigraphy (MPS) will improve image quality, interpretive certainty, and diagnostic accuracy. However, commonly used software packages for MPS usually include normal stress databases for non-attenuation corrected (NC) images but not for attenuation-corrected (AC) images. The aim of the study was to develop and compare different normal stress databases for MPS in relation to NC vs. AC images, male vs. female gender, and presence vs. absence of obesity. The principal hypothesis was that differences in mean count values between men and women would be smaller with AC than NC images, thereby allowing for construction and use of gender-independent AC stress database.MethodsNormal stress perfusion databases were developed with data from 126 male and 205 female patients with normal MPS. The following comparisons were performed for all patients and separately for normal weight vs. obese patients: men vs. women for AC; men vs. women for NC; AC vs. NC for men; and AC vs. NC for women.ResultsWhen comparing AC for men vs. women, only minor differences in mean count values were observed, and there were no differences for normal weight vs. obese patients. For all other analyses major differences were found, particularly for the inferior wall.ConclusionsThe results support the hypothesis that it is possible to use not only gender independent but also weight independent AC stress databases.

【 授权许可】

CC BY   
© Trägårdh et al; licensee BioMed Central Ltd. 2011