Perinatal mortality in rural Burkina Faso: a prospective community-based cohort study

BMC Pregnancy and Childbirth

Research Article

Emmanuel Zabsonré¹  Nicolas Meda¹  Abdoulaye Hama Diallo²  Thorkild Tylleskär³  Halvor Sommerfelt⁴  Simon Cousens⁵ 

[1] Centre MURAZ Research Institute, Ministry of Health/Burkina Faso, PO Box 390, Bobo-Dioulasso, Burkina Faso;Centre MURAZ Research Institute, Ministry of Health/Burkina Faso, PO Box 390, Bobo-Dioulasso, Burkina Faso;Centre for International Health (CIH), University of Bergen, Bergen, Norway;Centre for International Health (CIH), University of Bergen, Bergen, Norway;Centre for International Health (CIH), University of Bergen, Bergen, Norway;Division of Infectious Diseases Control, Norwegian Institute of Public Health, Oslo, Norway;London School of Hygiene and Tropical Medicine, Infectious Diseases Epidemiology Unit (IDEU), London, UK;

关键词: Health Facility;    Risk Ratio;    Perinatal Mortality;    Perinatal Death;    Verbal Autopsy;   

DOI  :  10.1186/1471-2393-10-45

 received in 2010-03-15, accepted in 2010-08-17,  发布年份 2010

来源: Springer

【 摘 要 】

BackgroundThere is a scarcity of reliable data on perinatal mortality (PNM) in Sub-Saharan Africa. The PROMISE-EBF trial, during which we promoted exclusive breastfeeding, gave us the opportunity to describe the epidemiology of PNM in Banfora Health District, South-West in Burkina Faso.Study objectivesTo measure the perinatal mortality rate (PNMR) in the PROMISE-EBF cohort in Banfora Health District and to identify potential risk factors for perinatal death.MethodsWe used data collected prospectively during the PROMISE-EBF-trial to estimate the stillbirth rate (SBR) and early neonatal mortality rate (ENMR). We used binomial regression with generalized estimating equations to identify potential risk factors for perinatal death.Results895 pregnant women were enrolled for data collection in the EBF trial and followed-up to 7 days after birth. The PNMR, the SBR and the ENMR, were 79 per 1000 (95% CI: 59-99), 54 per 1000 (95% CI: 38-69) and 27 per 1000 (95% CI: 9-44), respectively. In a multivariable analysis, nulliparous women (RR = 2.90, 95% CI: 1.6-5.0), primiparae mothers (RR = 2.20, 95% CI: 1.2-3.9), twins (RR = 4.0, 95% CI: 2.3-6.9) and giving birth during the dry season (RR = 2.1 95% CI: 1.3-3.3) were factors associated with increased risk of perinatal death. There was no evidence that risk of perinatal death differed between deliveries at home and at a health centreConclusionOur study observed the highest PNMR ever reported in Burkina. There is an urgent need for sustainable interventions to improve maternal and newborn health in the country.

【 授权许可】

CC BY   
© Diallo et al; licensee BioMed Central Ltd. 2010