Tracing the legacy of the early Hainan Islanders - a perspective from mitochondrial DNA

BMC Evolutionary Biology

Research Article

Min-Sheng Peng¹  Ya-Ping Zhang²  Jun-Dong He³  Hai-Xin Liu⁴ 

[1] State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, P.R. China;KIZ/CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming, P.R. China;Graduate School of the Chinese Academy of Sciences, Beijing, P.R. China;State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, P.R. China;KIZ/CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming, P.R. China;Laboratory for Conservation and Utilization of Bio-resources, Yunnan University, Kunming, P.R. China;State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, P.R. China;School of Life Science, University of Science and Technology of China, Hefei, P.R. China;KIZ/CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming, P.R. China;State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, P.R. China;School of Life Science, University of Science and Technology of China, Hefei, P.R. China;Program in Neuroscience, SUNY at Stony Brook, Stony Brook, New York, USA;

关键词: Last Glacial Maximum;    Modern Human;    Recent Gene Flow;    Hainan Islander;    Early People;   

DOI  :  10.1186/1471-2148-11-46

 received in 2010-09-30, accepted in 2011-02-15,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundHainan Island is located around the conjunction of East Asia and Southeast Asia, and during the Last Glacial Maximum (LGM) was connected with the mainland. This provided an opportunity for the colonization of Hainan Island by modern human in the Upper Pleistocene. Whether the ancient dispersal left any footprints in the contemporary gene pool of Hainan islanders is debatable.ResultsWe collected samples from 285 Li individuals and analyzed mitochondrial DNA (mtDNA) variations of hypervariable sequence I and II (HVS-I and II), as well as partial coding regions. By incorporating previously reported data, the phylogeny of Hainan islanders was reconstructed. We found that Hainan islanders showed a close relationship with the populations in mainland southern China, especially from Guangxi. Haplotype sharing analyses suggested that the recent gene flow from the mainland might play important roles in shaping the maternal pool of Hainan islanders. More importantly, haplogroups M12, M7e, and M7c1* might represent the genetic relics of the ancient population that populated this region; thus, 14 representative complete mtDNA genomes were further sequenced.ConclusionsThe detailed phylogeographic analyses of haplogroups M12, M7e, and M7c1* indicated that the early peopling of Hainan Island by modern human could be traced back to the early Holocene and/or even the late Upper Pleistocene, around 7 - 27 kya. These results correspond to both Y-chromosome and archaeological studies.

【 授权许可】

Unknown   
© Peng et al; licensee BioMed Central Ltd. 2011. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.