Culprit-only versus staged complete revascularization for patients with ST-segment elevation myocardial infarction and Multivessel disease: a retrospective cohort study

BMC Cardiovascular Disorders

Research Article

Chunyang Tian¹  Zhaoqing Sun¹  Yuanyuan Dong¹  Tongtong Yu¹  Zhijun Sun¹  Jiahe Zhu¹ 

[1] Department of Cardiology, Shengjing Hospital of China Medical University, Shenyang, Liaoning, People’s Republic of China;

关键词: Multivessel disease;    Revascularization;    ST-segment elevation myocardial infarction;   

DOI  :  10.1186/s12872-016-0365-5

 received in 2016-06-26, accepted in 2016-09-28,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundMultivessel disease (MVD) is common in patients with ST-segment elevation myocardial infarction (STEMI), but optimal treatment management remains undetermined.MethodsIn this retrospective cohort study, 602 consecutive STEMI patients with MVD were enrolled between January 1, 2010 and October 1, 2014. Three hundred and eighty-two patients underwent culprit-only revascularization and 220 underwent staged complete revascularization. Primary end points were a composite of cardiac mortality or nonfatal reinfarction.ResultsThe mean duration of follow-up was 35 months (12–71 months). Following multivariate analysis, staged complete revascularization was associated with a lower rate of the composite of cardiac mortality or nonfatal reinfarction [HR: 0.430, 95 % CI: 0.197–0.940, P = 0.034] and unplanned repeat revascularization [HR: 0.343, 95 % CI: 0.166–0.708, P = 0.004] compared with culprit-only revascularization.ConclusionsCompared with culprit-only revascularization, staged complete revascularization significantly reduced the rate of the composite of cardiac mortality or nonfatal reinfarction, and the need for unplanned repeat revascularization.

【 授权许可】

CC BY   
© The Author(s). 2016