Assessing health status in COPD. A head-to-head comparison between the COPD assessment test (CAT) and the clinical COPD questionnaire (CCQ)

BMC Pulmonary Medicine

Research Article

Ilaine Lopez¹  Thys van der Molen¹  Janwillem WH Kocks¹  Nikolaos Tzanakis²  Despoina Moraitaki²  Nikolaos Siafakas²  Konstantinos Karagiannis²  Ioanna G Tsiligianni³ 

[1] Department of General Practice, University Medical Centre Groningen, P.O 9700 AD, Antonius Deusinglaan 1, Groningen, The Netherlands;GRIAC research institute, University Medical Center Groningen, University of Groningen, P.O 9700 AD, Antonius Deusinglaan 1, Groningen, The Netherlands;Department of Thoracic Medicine, Medical School, University of Crete, P.O 71003, Heraklion, Crete, Greece;Department of Thoracic Medicine, Medical School, University of Crete, P.O 71003, Heraklion, Crete, Greece;Department of General Practice, University Medical Centre Groningen, P.O 9700 AD, Antonius Deusinglaan 1, Groningen, The Netherlands;GRIAC research institute, University Medical Center Groningen, University of Groningen, P.O 9700 AD, Antonius Deusinglaan 1, Groningen, The Netherlands;

关键词: Health status;    COPD Assessment Test (CAT);    Clinical COPD Questionnaire (CCQ);   

DOI  :  10.1186/1471-2466-12-20

 received in 2012-01-12, accepted in 2012-05-03,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundHealth status provides valuable information, complementary to spirometry and improvement of health status has become an important treatment goal in COPD management. We compared the usefulness and validity of the COPD Assessment Test (CAT) and the Clinical COPD Questionnaire (CCQ), two simple questionnaires, in comparison with the St. George Respiratory Questionnaire (SGRQ).MethodsWe administered the CAT, CCQ and SGRQ in patients with COPD stage I-IV during three visits. Spirometry, 6 MWT, MRC scale, BODE index, and patients perspectives on questionnaires were recorded in all visits. Standard Error of Measurement (SEM) was used to calculate the Minimal Clinical Important Difference (MCID) of all questionnaires.ResultsWe enrolled 90 COPD patients. Cronbach's alpha for both CAT and CCQ was high (0.86 and 0.89, respectively). Patients with severe COPD reported worse health status compared to milder subgroups. CAT and CCQ correlated significantly (rho =0.64, p < 0.01) and both with the SGRQ (rho = 0.65; CAT and rho = 0.77; CCQ, p < 0.01). Both questionnaires exhibited a weak correlation with lung function (rho = −0.35;CAT and rho = −0.41; CCQ, p < 0.01). Their reproducibility was high; CAT: ICC = 0.94 (CI 0.92-0.96), total CCQ ICC = 0.95 (0.92-0.96) and SGRQ = 0.97 (CI 0.95-0.98). The MCID calculated using the SEM method showed results similar to previous studies of 3.76 for the CAT, 0.41 for the CCQ and 4.84 for SGRQ. Patients suggested both CAT and CCQ as easier tools than SGRQ in terms of complexity and time considerations. More than half of patients preferred CCQ instead of CAT.ConclusionsThe CAT and CCQ have similar psychometric properties with a slight advantage for CCQ based mainly on patients’ preference and are both valid and reliable questionnaires to assess health status in COPD patients.

【 授权许可】

CC BY   
© Tsiligianni et al; licensee BioMed Central Ltd. 2012