Cervical precancerous changes and selected cervical microbial infections, Kiambu County, Kenya, 2014: a cross sectional study

BMC Infectious Diseases

Research Article

Margaret Muturi¹  Lucy Kamau²  Evalyne Wambui Kanyina³ 

[1]Department of Medical Laboratory Sciences, Kenyatta University, School of Medicine, P. O. Box 43844-00100, Nairobi, Kenya

[2]Department of Zoological Sciences, Kenyatta University, School of Pure and Applied Sciences, P. O. Box 43844-00100, Nairobi, Kenya

[3]Ministry of Health, P. O. Box 30016-00100, Nairobi, Kenya

关键词: Cervical precancerous changes;    Cervical intraepithelial neoplasia (CIN);    Cervical microbial infections;    Pap smear;    Kenya;   

DOI  :  10.1186/s12879-017-2747-4

 received in 2017-01-31, accepted in 2017-09-19,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundCervical cancer is the predominant cancer among women in Kenya and second most common in women in developing regions. Population-based cytological screening and early treatment reduces morbidity and mortality associated with the cancer. We determined the occurrence of cervical precancerous changes and cervical microbial infections (Trichomonas vaginalis, Candida albicans, Neisseria gonorrhea and Actinomyces) among women attending Family Health Option Kenya (FHOK) clinic in Thika.MethodsThis was a hospital based cross sectional study among women attending reproductive health screening clinic from November 2013 to January 2014. Cervical Intraepithelial Neoplasia (CIN) I, II, III, cervical cancer and microbial infection (Actinomyces, Trichomonas vaginalis and Yeast cells) diagnosis was based on Pap smear screening test and High Vaginal Swab wet preparation microscopy. Neisseria gonorrhea was diagnosed through Gram staining. Socio-demographic and reproductive health data was collected using a structured questionnaire administered to the study participants and analyzed using Epi Info version 3.5.1.ResultsOf the 244 women screened, 238 (97.5%) presented with cervical inflammation, 80 (32.8%) cervical microbial infections and 12 (4.9%) cervical precancerous changes; 10 (83.3%) with CIN I and 2 (16.7%) CIN II. Of the 80 cervical microbial infections, 62 (77.5%) were yeast cell and 18 (22.5%) T. vaginalis. One thirty four (55%) participants had no history of Pap smear screening of which 84 (62.7%) were 20–40 years. Use of IUCDs (OR: 2.47, 95% CI 1.3–4.6) was associated with cervical inflammation.ConclusionsCIN I was the predominant cervical precancerous change. There is need to scale up cervical screening test to capture all categories of women.

【 授权许可】

CC BY   
© The Author(s). 2017