Binge drinking and total alcohol consumption from 16 to 43 years of age are associated with elevated fasting plasma glucose in women: results from the northern Swedish cohort study

BMC Public Health

Research Article

Karina Nygren¹  Olov Rolandsson¹  Anne Hammarström² 

[1] Department of Public Health and Clinical Medicine, Umeå University, 90187, Umeå, SE, Sweden;Department of Public Health and Clinical Medicine, Umeå University, 90187, Umeå, SE, Sweden;Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden;

关键词: Glucose metabolism;    Alcohol;    Gender;    Cohort study;   

DOI  :  10.1186/s12889-017-4437-y

 received in 2016-09-12, accepted in 2017-05-15,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundStudies have indicated that moderate alcohol consumption is associated with lower incidence of diabetes in women. However, not only the amount but also the drinking pattern could be of importance when assessing the longitudinal relation between alcohol and glucose. Also, there is a lack of studies on alcohol use beginning in adolescence on adult glucose levels. The aim was to examine the association between total alcohol consumption and binge drinking between ages 16 and 43 and fasting plasma glucose at age 43.MethodsData were retrieved from a 27-year prospective cohort study, the Northern Swedish Cohort. In 1981, all 9th grade students (n = 1083) within a municipality in Sweden were invited to participate. There were re-assessments at ages 18, 21, 30 and 43. This particular study sample consisted of 897 participants (82.8%). Fasting plasma glucose (mmol/L) was measured at a health examination at age 43. Total alcohol consumption (in grams) and binge drinking were calculated from alcohol consumption data obtained from questionnaires.ResultsDescriptive analyses showed that men had higher levels of fasting plasma glucose as compared to women. Men also reported higher levels of alcohol consumption and binge drinking behavior. Linear regressions showed that total alcohol consumption in combination with binge drinking between ages 16 and 43 was associated with elevated fasting plasma glucose at age 43 in women (beta = 0.14, p = 0.003) but not in men after adjustment for BMI, hypertension and smoking at age 43.ConclusionsOur findings indicate that reducing binge drinking and alcohol consumption among young and middle-aged women with the highest consumption might be metabolically favorable for their future glucose metabolism.

【 授权许可】

CC BY   
© The Author(s). 2017