Effect of periodontitis on the development of osteoporosis: results from a nationwide population-based cohort study (2003–2013)

BMC Women's Health

Research Article

Hye-In Kweon¹  Young-Taek Kim¹  Jae-Hong Lee²  Seong-Ho Choi³  Jung-Kyu Choi⁴  Eun-Cheol Park⁵ 

[1] Department of Periodontology, National Health Insurance Service Ilsan Hospital, Goyang, Korea;Department of Periodontology, Wonkwang University Daejeon Dental Hospital, Wonkwang University College of Dentistry, 77, Dunsan-ro, Seo-gu, 35233, Daejeon, Korea;Department of Periodontology, Yonsei University College of Dentistry, 50 Yonsei-ro, Seodaemun-gu, 03722, Seoul, Korea;Department of Periodontology, Yonsei University College of Dentistry, Seoul, Korea;Department of Preventive Medicine and Institute of Health Services Research, Yonsei University College of Medicine, Seoul, Korea;Institute of Health Services Research, Yonsei University College of Medicine, Seoul, Korea;

关键词: Osteoporosis;    Periodontitis;    Cohort study;    Female;    Middle-aged;   

DOI  :  10.1186/s12905-017-0440-9

 received in 2016-10-26, accepted in 2017-08-28,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundThe prevalence of osteoporosis associated with the aging process is anticipated to increase along with the rising aging population. Periodontitis that the most common chronic infections of humankind is considered the risk factor for osteoporosis. The aim of this study was to identify the association between osteoporosis and periodontitis using a population-based cohort.MethodsThe case group was defined as patients diagnosed with periodontitis and treated with subgingival curettage, root conditioning, periodontal flap operation, bone grafting for alveolar bone defects, and guided tissue regeneration. Case and control groups matched for gender, age, household income, type of social security, disability, and residential area were generated. A Cox proportional hazard model was constructed to examine the difference in the development of osteoporosis between the case and control groups. The final sample included 13,464 participants.ResultsThe incidence of osteoporosis was 1.1% in males and 15.8% in females during a 10-year period. The risk factors for osteoporosis in males were increasing age and Charlson Comorbidity Index score. Periodontitis was not associated with the development of osteoporosis in males. The risk factors for osteoporosis in females were increasing age, body mass index, Charlson Comorbidity Index score, diabetes, and periodontitis. Women with periodontitis were more likely to also develop osteoporosis (HR: 1.22, 95% CI: 1.01–1.48).ConclusionsPeriodontitis has an effect on the development of osteoporosis in females. Managing good teeth is required for the prevention and delay of osteoporosis. This includes dental examinations, regular cleanings and gum treatment.

【 授权许可】

CC BY   
© The Author(s). 2017